Facile preparation of biocompatible poly(l-lactic acid)-modified halloysite nanotubes/poly(ε-caprolactone) porous scaffolds by solvent evaporation of Pickering emulsion templates

Hu, Yang; Liu, Shuifeng; Li, Xin; Yuan, Teng; Zou, Xiuju; He, Yinyan; Dong, Xiaoting; Zhou, Wuyi

doi:10.1007/s10853-018-2588-6

Cited by 19 publications

(15 citation statements)

References 38 publications

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“…The recently developed non-flow-through catalysis applications include the catalytic reduction of 4-nitrophenol to 4-aminophenol, the catalytic transformation of cellulose into 5-hydroxymethylfurfural, and biocatalytic waste stream upcycling . Encapsulation and release PH applications also continue to be of interest and include the encapsulation of thermal energy storage-release phase change materials ,, and the release of the antibacterial drug enrofloxacin and cinnamon oil (which also exhibits antibacterial activity) …”

Section: Perspectives and Prognosticationsmentioning

confidence: 99%

Emulsion Templating: Porous Polymers and Beyond

et al. 2019

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Emulsion templating presently extends far beyond the original hydrophobic porous polymers that were synthesized within surfactant-stabilized water-in-oil high internal phase emulsions (HIPEs) by using free radical polymerization. This Perspective presents the extraordinary versatility of emulsion templating that has emerged with the growing numbers of HIPE systems, HIPE stabilization strategies, monomers, polymerization chemistries, multicomponent materials, and surface functionalities. Emulsion templating now goes far beyond "porous polymers" by encompassing the encapsulation of aqueous solutions, ionic melts, and organic liquids as well as by encompassing porous carbons and porous inorganics. Herein, we present comprehensive pictures of the state-of-the-art, of the prospective large-scale and niche applications, of the advantages and challenges for industrial scale-up, and of the crucial directions that should be pursued in future work. We demonstrate that it is emulsion templating's considerable and versatile parameter space that offers opportunities for pioneering work, breakthrough innovations, scientific/engineering achievements, and industrial adoption.

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Section: Perspectives and Prognosticationsmentioning

confidence: 99%

Emulsion Templating: Porous Polymers and Beyond

et al. 2019

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“…The solvent evaporation technique was employed to generate porous PCL-mHNT nanocomposite scaffolds from w/o Pickering emulsion templates (low to high internal phase content) comprising mHNT dispersion in the PCL solution (M w = 80 000 g mol À1 , 10 wt% in DCM) as the continuous phase. 87 Pickering emulsions were prepared at 3500 rpm in a vortex mixture, solidified by a solvent and water evaporation at room temperature in a fume hood and finally under vacuum. The microstructure, porosity and antibacterial drug (enrofloxacin) release kinetics of emulsion templated PCL-mHNT nanocomposite scaffolds were efficiently tailored by varying the mHNT loadings and volume ratios of the dispersed to continuous phase.…”

Section: Aqueous Hipe Templatesmentioning

confidence: 99%

Emulsion templated scaffolds of poly(ε-caprolactone) – a review

et al. 2022

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“…In this study, the antibacterial drug ENR was used to monitor the drug loading and in vitro release behavior of MPB scaffolds. The loading efficiencies of ENR-loaded scaffolds were determined by the extraction method reported in our previous work [41], and the detailed procedures were displayed in the Supplementary Material. The ENR loading efficiencies for scaffolds P 3 H 7.5 S 2 , P 6 H 7.5 S 2 and P 9 H 7.5 S 2 were 97.9%, 96.9% and 99.3%, respectively, close to the theoretical limit.…”

Section: In Vitro Drug Release and Antibacterial Activity Testingmentioning

confidence: 99%

3D printing of Pickering emulsion inks to construct poly(D,L-lactide-co-trimethylene carbonate)-based porous bioactive scaffolds with shape memory effect

Wang

Gao

et al. 2020

J Mater Sci

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Biocompatible and bioactive scaffolds with multiscale porosity, shape memory effect and drug delivery performance are highly promising in bone tissue engineering applications within the approach of minimally invasive surgical implantation. In this study, we report an effective method to fabricate multiscale porous bioactive (MPB) scaffolds with shape memory effect by freeze drying of 3D printed high internal phase Pickering emulsion (Pickering HIPE) templates stabilized by hydrophobically modified hydroxyapatite and silica nanoparticles. MPB scaffolds containing a shape memory polymer matrix of poly(D,L-lactideco-trimethylene carbonate) display high porosity and fully interconnected filament networks with multiscale pore structures. The in vitro biomineralization study verifies that MPB scaffolds are bioactive with the apatite formation ability. The thermal property testing shows that the glass transition temperature of MPB scaffolds is easily tuned to fall between 45.9 and 49.1°C by varying the HIPE composition. Moreover, MPB scaffolds exhibit observable shape memory properties with fast shape recovery. The antibacterial drug enrofloxacin can be efficiently loaded into MPB scaffolds and then released in a sustained manner displaying effective antimicrobial effect. Furthermore, cell culture assays confirm that MPB scaffolds could sustain the cell growth, proliferation and osteogenic differentiation, indicating the cytocompatibility and osteoinduction activity of MPB scaffolds. Therefore, combining freeze drying with 3D printing Handling Editor: Annela M. Seddon.

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Facile preparation of biocompatible poly(l-lactic acid)-modified halloysite nanotubes/poly(ε-caprolactone) porous scaffolds by solvent evaporation of Pickering emulsion templates

Cited by 19 publications

References 38 publications

Emulsion Templating: Porous Polymers and Beyond

Emulsion Templating: Porous Polymers and Beyond

Emulsion templated scaffolds of poly(ε-caprolactone) – a review

3D printing of Pickering emulsion inks to construct poly(D,L-lactide-co-trimethylene carbonate)-based porous bioactive scaffolds with shape memory effect

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