Facile preparation of a highly sensitive non-enzymatic glucose sensor based on the composite of Cu(OH)2 nanotubes arrays and conductive polypyrrole

Label-free electrochemical aptasensor for rapid detection of SARS-CoV-2 spike glycoprotein based on the composite of Cu(OH)2 nanorods arrays as a high-performance surface substrate

“…Among the various methods of synthesizing copper nanoparticles, the in-situ growth method is an attractive method because nanoparticles can be synthesized directly on the surface of electrode without the need for adhesives and organic solvents, which is fast and facile synthesis procedure and has the ability to morphological controllability and thickness. Also, in comparison with traditional methods of electrode modification, such as drop or film casting, this method prevents the aggregation of nanoparticles and is uniformly placed on the electrode surface, leading to increased stability, conductivity and their active surface [54] , [55] . Cu(OH) 2 NRs, in addition to providing an extremely large surface area for aptamer strings further loading, also act as a suitable electroactive substrate owing to the large amount of copper placed on the electrode surface and the creation of an excellent cathodic current in the phosphate buffer, therefore, it can be a unique choice as a platform for the preparation of label free and ultrasensitive electrochemical aptasensors.…”

“…Cu(OH) 2 NRs, in addition to providing an extremely large surface area for aptamer strings further loading, also act as a suitable electroactive substrate owing to the large amount of copper placed on the electrode surface and the creation of an excellent cathodic current in the phosphate buffer, therefore, it can be a unique choice as a platform for the preparation of label free and ultrasensitive electrochemical aptasensors. Cu(OH) 2 NRs have shown significant performance in a variety of applications including electrocatalysis, and energy storage because of their good electrocatalytic performance and high surface area but as far as we know, they have not yet been used to improve the performance of electrochemical biosensors [54] , [55] , [56] , [57] , [58] .…”

Design of a Flexible Enzyme‐less Glucose Sensor Based on Non‐woven Fabric and Fe‐Doped CuO Nanocomposite

“…The increase in oxidation current when using an NWF−Fe/CuO−CPE indicates typical electrocatalytic activity for glucose oxidation. According to the previous research, [40–42] the most appropriate and feasible mechanism for glucose oxidation is at the NWF−Fe/CuO−CPE in basic media, as indicated by the following reactions: $$$\vcenter{\openup.5em\halign{$\displaystyle{#}$\cr {\rm CuO}+{\rm OH}{^{- }}\rightarrow {\rm CuOOH}+{\rm e}{^{- }}\hfill\cr}}$$$ $$$\vcenter{\openup.5em\halign{$\displaystyle{#}$\cr {\rm 2CuOOH}+{\rm Glucose}+{\rm e}{^{- }}\rightarrow {\rm Gluconolactone}+{\rm 2CuO}+{\rm H}{_{2}}{\rm O}\hfill\cr}}$$$ $$$\vcenter{\openup.5em\halign{$\displaystyle{#}$\cr {\rm Gluconolactone}\rightarrow {\rm Gluconic}\ {\rm acid}\ ({\rm hydrolysis})\hfill\cr}}$$$ …”

“…The increase in oxidation current when using an NWFÀ Fe/CuOÀ CPE indicates typical electrocatalytic activity for glucose oxidation. According to the previous research, [40][41][42] the most appropriate and feasible mechanism for glucose oxidation is at the NWFÀ Fe/CuOÀ CPE in basic media, as indicated by the following reactions:…”

The latest trends in the design of electrochemical biosensors for the diagnosis and monitoring of diabetes mellitus

“…Copper(II) hydroxide nanotubes prepared by electrodeposition of Cu clusters on a thin fi lm of electropolymerized polypyrrole were used to manufacture an amperometric glucose sensor by Manafi -Yeldaghermani and co-authors (2021) (23). Amorphous Ni-Co-Fe hydroxide nanospheres with a homogeneous distribution of metals are fabricated directly on a graphite substrate by an electrodeposition method in the work of Li and Zhao (2019) (24).…”