Facile One-Pot Synthesis and Morphological Control of Asymmetric Superparamagnetic Composite Nanoparticles

Wang, Yilong; Xu, Hong; Ma, Yongsheng; Guo, Fangfang; Wang, Feng; Shi, Donglu

doi:10.1021/la200749w

Cited by 45 publications

(41 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…6 A similar partial encapsulation by silica around a core particle was demonstrated by Feyen et al 12 The silica partially wrapped around an asymmetric iron oxide/cPS core, wherein the iron oxide surface was carboxylatemodified, while the cPS was not. While the authors did not report the carboxylate surface density, it was enough to form a partial silica shell.…”

Section: ■ Results and Discussionmentioning

confidence: 53%

Asymmetric Colloidal Janus Particle Formation Is Core-Size-Dependent

Landon

Printz

et al. 2015

Langmuir

View full text Add to dashboard Cite

Colloidal particles with asymmetric surface chemistry (Janus particles) have unique bifunctional properties. The size of these particles is an important determinant for their applications in diverse fields from drug delivery to chemical catalysis. The size of Janus particles, with a core surface coated with carboxylate and a partially encapsulating silica shell, depends upon several factors, including the core size and the concentration of carboxylate coating. The role of the carboxylate coating on the Janus particle size is well-understood; however, the role of the core size is not well defined. The role of the carboxylated polystyrene (cPS) core size on the cPS-silica Janus particle morphology (its size and shape) was examined by testing two different silica sizes and five different cPS core sizes. Results from electron microscopy (EM) and dynamic light scattering (DLS) analysis indicate that the composite cPS-silica particle acquires two distinct shapes: (i) when the size of the cPS core is much smaller than the non-cPS silica (b-SiO2) sphere, partially encapsulated Janus particles are formed, and (ii) when the cPS core is larger than or equal to the b-SiO2 sphere, a raspberry-like structure rather than a Janus particle is formed. The cPS-silica Janus particles of ∼100-500 nm size were obtained when the size of the cPS core was much smaller than the non-cPS silica (b-SiO2) sphere. These scalable nanoscale Janus particles will have wide application in a multifunctional delivery platform and catalysis.

show abstract

Section: ■ Results and Discussionmentioning

confidence: 53%

Asymmetric Colloidal Janus Particle Formation Is Core-Size-Dependent

Landon

Printz

et al. 2015

Langmuir

View full text Add to dashboard Cite

show abstract

“…The average molecular weights of the PS block and P2VP block were 8200 and 8300, respectively. Fe(CO) 5 , oleic acid, oleylamine, MUA, isopropanol, ethanol, hexane, toluene and THF were of analytical grade and used as-received.…”

Section: Methodsmentioning

confidence: 99%

“…[4] To date, asymmetric particles embedding superparamagnetic materials have attracted great interest because of their potential applications. [5] However, it still remains a challenge to prepare asymmetric multicomponent magnetic inorganic/polymer composite NPs.…”

Section: Introductionmentioning

confidence: 99%

A Simple Route to Asymmetric Composite Particles via Co-assembly of Block Copolymer and Inorganic Nanoparticles in Solution

Li¹,

Li²,

Li³

et al. 2016

Proceedings of the 2nd Annual International Conference on Advanced Material Engineering (AME 2016)

View full text Add to dashboard Cite

Abstract.A novel approach to organic-inorganic asymmetric particles through the co-assembly of block copolymers (BCs) and magnetic Fe 3 O 4 nanoparticles (NPs) in solution is demonstrated. When 11-mercaptoundecanoic acid (MUA) modified Fe 3 O 4 NPs and an amphiphilic block copolymer polystyrene-b-poly (2-vinylpyridine) (PS-b-P2VP) were mixed in THF, asymmetric composite particles formed due to the hydrogen bonding interactions between -SH groups of the MUA molecules coated on Fe 3 O 4 NPs and P2VP blocks. The asymmetric particles obtained by this facile approach may have potential applications in biomedical areas.

show abstract

“…Therefore, there is a critical need to develop novel synthesis route to synthesize such ternary magnetic composites with anisotropic surface property and shape via phase separation. Wang and coworkers 34 have synthesized Janus magnetic composite particles (JMCPs) with high anisotropy and magnetite content consisting of iron oxide, silica, and polystyrene by phase separation in a combining miniemulsion polymerization with a sol-gel technique. This approach eliminates the multistep procedures needed in the preparation of composites with magnetic contents.…”

Section: Janus Fe 3 O 4 @Silica/polystyrene Composites Via Phase Sepamentioning

confidence: 99%

Janus Nanostructures and Their Bio-medical Applications

Wang¹,

Wang²

2014

Bio-Inspired Nanomaterials and Applications

Self Cite

View full text Add to dashboard Cite

Nanotechnology has great potential in bio-medicine, leading to tremendous efforts in gene transfection, drug delivery, cell targeting and hyperthermia. As researchers gain familiarity with homogeneous nanomaterials, more attention is drawn to Janus nanostructure, an emerging new material with two or more distinct properties. With the uniqueness in asymmetry, Janus nanomaterials offer more possibilities for assembling multifunctional carriers. In this chapter, the synthesis of ternary Janus system of silica, Fe 3 O 4 and polystyrene is introduced. A relatively easy method of combining miniemulsion and sol-gel is employed. The reaction mechanism is discussed with controllable morphology obtained. Dual surface functionalities are explored by selectively conjugating targeting group and anti-cancer drug. In vitro drug release profi les indicate a pH-responsive fashion. Cell study proves that the Janus nanocomposites successfully combine targeting and controlled drug release, achieving higher drug effi cacy. Future endeavors will focus on structure novelty as well as fabrication simplifi cation and scaling up. With its potential for higher integration, Janus nanostructures can well-serve as a versatile platform for biomedical applications.Bio-Inspired Nanomaterials and Applications Downloaded from www.worldscientific.com by KAINAN UNIVERSITY on 02/03/15. For personal use only.

show abstract

Facile One-Pot Synthesis and Morphological Control of Asymmetric Superparamagnetic Composite Nanoparticles

Cited by 45 publications

References 45 publications

Asymmetric Colloidal Janus Particle Formation Is Core-Size-Dependent

Asymmetric Colloidal Janus Particle Formation Is Core-Size-Dependent

A Simple Route to Asymmetric Composite Particles via Co-assembly of Block Copolymer and Inorganic Nanoparticles in Solution

Janus Nanostructures and Their Bio-medical Applications

Contact Info

Product

Resources

About