Facile Intramolecular Cyclization of N‐(2‐Hydroxybenzoyl)hydrazones to N,N′‐Diacetyl Benzo‐1,3,4‐oxadiazepine Derivatives

Abstract

Af acile synthesis of seven-membered benzo-1,3,4-oxadiazepines through one-step intramolecular cyclization of N-(2-hydroxybenzoyl)hydrazones has been established. The catalytic and substituent effects on the reactivity of this intramolecular cyclization were investigated. Through this strategy,aseries of benzo-1,3,4-oxadiazepine derivativesw ereprepared (with yields up to 83 %).