Facile and Green Synthesis of Novel Fluorescent Carbon Quantum Dots and Their Silver Heterostructure: An <i>In Vitro</i> Anticancer Activity and Imaging on Colorectal Carcinoma

Mishra, Snehasis; Das, Kaustav; Chatterjee, Sabyasachi; Sahoo, Panchanan; Kundu, Sudip; Pal, M.; Bhaumik, Asim; Ghosh, Chandan Kumar

doi:10.1021/acsomega.2c04964

Cited by 18 publications

(11 citation statements)

References 72 publications

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“…The decrease in the average lifetime is mainly due to an increase in the nonradiative decay rates of the nanocomposites. This may be due to the noncovalent complex formation between CDs and nanoparticles (AgNP and AuNP). , …”

Section: Resultsmentioning

confidence: 99%

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Carbon-Dot-Decorated Silver and Gold Nanocomposites for Antibacterial Activity and Degradation of Organic Dyes

Ghosh,

Bairagi,

Hazra

et al. 2023

ACS Appl. Nano Mater.

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A hydrothermal process has been used to prepare highly fluorescent green-emitting crystalline carbon dots (CDs) at 200 °C using Bismarck brown dye. The HR-TEM image shows the clear lattice fringes with d-spacing values of 0.23 and 0.33 nm corresponding to the (100) and (002) planes, respectively, indicating the crystalline nature of carbon dots. These as-synthesized carbon dots have been successfully used to make two different nanocomposite systems, consisting of silver and gold nanoparticles with carbon dots. Here carbon dots act as a reducing agent in the presence of UV light/blue LED light to synthesize silver and gold nanoparticles from their respective metal salts. In the presence of silver and gold nanoparticles, the fluorescence of carbon dots was almost quenched in their respective nanocomposite systems. These carbon dots and carbon-dot-decorated silver/gold nanocomposite systems have been well characterized by various analytical techniques including UV–vis spectroscopy, transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Fourier-transformed infrared spectroscopy (FT-IR), and X-ray diffraction spectroscopic (XRD) study. Interestingly, carbon-dot-containing silver nanoparticles (CD-AgNP) exhibit a potential antibacterial activity against Gram-positive (Staphylococcus aureus, Bacillus subtilis) and Gram-negative (Escherichia coli, Pseudomonas aeruginosa) bacteria. The CD-AgNP shows a maximum inhibition zone diameter of 20, 15, 14, and 20 mm and having a minimum inhibitory concentration (MIC) of 12–16, 12–16, 16–25, and 16–25 μg/mL for S. Aureus, E. coli, B. subtilis, and P. aeruginosa, respectively, while the gold nanocomposite (CD-AuNP) has been utilized for the degradation of hazardous organic dyes including methyl orange (MO), Congo red (CR), and Evan’s blue (EB) within 10–12 min.

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Section: Resultsmentioning

confidence: 99%

“…This may be due to the noncovalent complex formation between CDs and nanoparticles (AgNP and AuNP). 29,30 Morphology Study. Field electron gun transmission electron microscopic (FEG-TEM) imaging was performed to get morphological insight into the carbon dots.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

Carbon-Dot-Decorated Silver and Gold Nanocomposites for Antibacterial Activity and Degradation of Organic Dyes

Ghosh,

Bairagi,

Hazra

et al. 2023

ACS Appl. Nano Mater.

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“…After centrifugation, they were plated at a required density to permit them to re-equilibrate before further investigation. 28…”

Section: Methodsmentioning

confidence: 99%

“…After centrifugation, they were plated at a required density to permit them to re-equilibrate before further investigation. 28 In vitro T 1 -and T 2 -weighted cellular MRI contrast measurement…”

Section: Cell Culturementioning

confidence: 99%

“…Fluorophore-conjugated secondary antibodies were diluted 1 : 100 in the blocking solution and incubated for another 2 h. The slides were then counterstained with DAPI for 10 min and mounted with the ProLong Anti-fade Reagent (Molecular Probe, Eugene, OR, USA). 28 Staining images of the double immunofluorescence were examined using a confocal laser-scanning microscope (FV 10i, Olympus, Japan).…”

Section: Confocal Microscopymentioning

confidence: 99%

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Quercetin@Gd³⁺ doped Prussian blue nanocubes induce the pyroptotic death of MDA-MB-231 cells: combinational targeted multimodal therapy, dual modal MRI, intuitive modelling of r₁–r₂ relaxivities

Sahoo¹,

Jana²,

Kundu³

et al. 2023

J. Mater. Chem. B

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MOF@Au NPs/aptamer fluorescent probe for the selective and sensitive detection of thiamethoxam

Yuan,

Li,

et al. 2023

Luminescence

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The luminescence performance of fluorescent reagents plays a crucial role in fluorescence analysis. Therefore, in this study, a novel bi‐ligand Zn‐based metal–organic framework, Au nanoparticle (NP) fluorescent material was synthesized using a hydrothermal method with Zn as the metal source. Simultaneously, a DNA aptamer was introduced as a molecular recognition element to develop a Zn‐based MOF@Au NPs/DNA aptamer fluorescent probe for the ultra‐trace detection of thiamethoxam residues in agricultural products. The probe captured different concentrations of the target molecule, thiamethoxam, through the DNA aptamer, causing a conformational change in the DNA aptamer and bursting the fluorescence of the probe, therefore establishing a fluorometric method for thiamethoxam detection. This method is highly sensitive due to the excellent luminescence properties of the Zn‐based MOF@Au NPs, and the DNA aptamer can specifically recognize thiamethoxam, offering high selectivity. The linear range of the method was 2.5–6000 × 10−11 mol L−1, with a detection limit of 8.33 × 10−12 mol L−1. This method was applied to the determination of actual samples, such as bananas, and the spiked recovery rate was found to be in the range 84.05–109.07%. Overall, the proposed probe has high sensitivity, high selectivity, and easy operation for the detection of thiamethoxam residues in actual samples.

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Facile and Green Synthesis of Novel Fluorescent Carbon Quantum Dots and Their Silver Heterostructure: An In Vitro Anticancer Activity and Imaging on Colorectal Carcinoma

Cited by 18 publications

References 72 publications

Carbon-Dot-Decorated Silver and Gold Nanocomposites for Antibacterial Activity and Degradation of Organic Dyes

Carbon-Dot-Decorated Silver and Gold Nanocomposites for Antibacterial Activity and Degradation of Organic Dyes

Quercetin@Gd³⁺ doped Prussian blue nanocubes induce the pyroptotic death of MDA-MB-231 cells: combinational targeted multimodal therapy, dual modal MRI, intuitive modelling of r₁–r₂ relaxivities

MOF@Au NPs/aptamer fluorescent probe for the selective and sensitive detection of thiamethoxam

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Facile and Green Synthesis of Novel Fluorescent Carbon Quantum Dots and Their Silver Heterostructure: An In Vitro Anticancer Activity and Imaging on Colorectal Carcinoma

Cited by 18 publications

References 72 publications

Carbon-Dot-Decorated Silver and Gold Nanocomposites for Antibacterial Activity and Degradation of Organic Dyes

Carbon-Dot-Decorated Silver and Gold Nanocomposites for Antibacterial Activity and Degradation of Organic Dyes

Quercetin@Gd3+ doped Prussian blue nanocubes induce the pyroptotic death of MDA-MB-231 cells: combinational targeted multimodal therapy, dual modal MRI, intuitive modelling of r1–r2 relaxivities

MOF@Au NPs/aptamer fluorescent probe for the selective and sensitive detection of thiamethoxam

Contact Info

Product

Resources

About

Quercetin@Gd³⁺ doped Prussian blue nanocubes induce the pyroptotic death of MDA-MB-231 cells: combinational targeted multimodal therapy, dual modal MRI, intuitive modelling of r₁–r₂ relaxivities