Facile Access to α-Substituted β-Thio Enals from 1,2,3-Triazines and Thiols

Abstract

Herein, we report a chemoselective cascade addition reaction, which started from 1,2,3-triazines and thiols, and can obtained several different α-substituted β-thio enals and their derivatives in a green and efficient synthesis. In terms of applications, readily available substrates, diverse products, and a mild reaction system make this strategy highly attractive.