Facial sensibility of patients with trigeminal neuralgias

Siviero, Mariana; Alvarez, Fábio Kurogi; Okada, Massako; Teixeira, Manoel Jacobsen; Siqueira, José Tadeu Tesseroli de; Siqueira, Sílvia Regina Dowgan Tesseroli de

doi:10.1016/j.clineuro.2010.11.012

Cited by 17 publications

(27 citation statements)

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“…Trigeminal afferents are originated from all orofacial tissues, the dura, nasal tissues, corneal surface, and facial skin [34]. The diagnostic criteria form of ITN does not include neurological abnormalities, but light changes in sensory function have been reported [3,10,30,31,[35][36][37]. In this study, thermal detection thresholds (warm and cold) and tactile detection were higher in the group of patients (Fig.…”

Section: Gustatory Olfactory and Somatosensory Evaluationmentioning

confidence: 82%

“…Since the beginning of XX century, it has been observed that the trigeminal lesion causes changes in taste, and clinical evidences of this interaction can be observed in gustatory and olfactory abnormalities in patients with orofacial neuropathic pain in several studies [10,27,30,31]. Siviero and collaborators [10] observed these abnormalities also in other patients with orofacial neuropathic pain, and concluded that the gustatory and olfactory perceptions can be altered in chronic trigeminal pain and after trigeminal surgical procedures.…”

Section: Gustatory Olfactory and Somatosensory Evaluationmentioning

confidence: 94%

“…These differences show evidence for pathophysiological mechanisms and for the hypothesis of demielinization at the entry zone of the trigeminal root, inducing local neuroplasticity (e.g. expression changes in sodium and calcium channels and facilitation of depolarization) [31].…”

Section: Gustatory Olfactory and Somatosensory Evaluationmentioning

confidence: 99%

See 2 more Smart Citations

Functional and sensory evaluation of patients with idiopathic trigeminal neuralgia: Comparison with controls

Ichida

Silva

Teixeira

et al. 2015

Clinical Neurology and Neurosurgery

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Section: Gustatory Olfactory and Somatosensory Evaluationmentioning

confidence: 82%

Section: Gustatory Olfactory and Somatosensory Evaluationmentioning

confidence: 94%

See 1 more Smart Citation

Functional and sensory evaluation of patients with idiopathic trigeminal neuralgia: Comparison with controls

Ichida

Silva

Teixeira

et al. 2015

Clinical Neurology and Neurosurgery

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“…34 Maier et al 19 reported increased MDT less frequently (16.3%), whereas increased CDT (38.1%), WDT (25%), and MPT (12%) were the most prominent regarding loss of function. 19,31 In contrast, in our study, increased CDT and WDT were rarely detected.…”

Section: Subclinical Hypoesthesiamentioning

confidence: 96%

Quantitative sensory testing in classical trigeminal neuralgia—a blinded study in patients with and without concomitant persistent pain

Younis

Maarbjerg

Reimer

et al. 2016

Pain

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The diagnostic criteria of the third International Classification of Headache Disorders state that there should be no neurological deficits in patients with classical trigeminal neuralgia (TN) at clinical examination. However, studies demonstrating sensory abnormalities at bedside examination in TN patients have questioned this. Our aim was to examine whether TN patients without sensory abnormalities at neurological examination have sensory abnormalities at quantitative sensory testing (QST) and whether there were any QST differences between TN with and without concomitant persistent pain. Thirty-six TN patients were investigated with the standardized QST protocol by the German Research Network on Neuropathic Pain. The investigators were blinded to presence of concomitant persistent pain and symptomatic side. Based on comparison to the German Research Network on Neuropathic Pain controls, z scores were calculated to process frequency analyses and Z-profiles. We found increased mechanical detection threshold on the symptomatic side (47.2% vs 0%, P = 0.008), asymptomatic side (33.3% vs 0%, P = 0.011), and hand (36% vs 0%, P < 0.001) in TN compared with controls. The Z-profiles demonstrated increased mechanical detection threshold on the symptomatic side compared with the asymptomatic side (-2.980 vs -2.166, P = 0.040). Thermal and mechanical hyperalgesia was detected bilaterally in the face and the hand. Trigeminal neuralgia patients with concomitant persistent pain tended to have higher mean z score values compared to TN with purely paroxysmal pain indicative of decreased detection thresholds. Trigeminal neuralgia patients with no sensory abnormalities at neurological examination had generalized subclinical hypoesthesia, which was more pronounced on the symptomatic side, and thermal and mechanical hyperalgesia. This could indicate pain-induced hypoesthesia and sensitization induced by central mechanisms.

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“…The importance in the neuropathic pain of this body area is crucial. Besides the information in this paper, there are other types of QST in the market, such as Somedic equipments, and the current literature in the orofacial evaluation indicates that somatosensory aspects but also gustative and olfactory functions can be affected by chronic pain [6][7][8][9][10][11][12][13] . It is also an important tool to follow the progress of sensory loss after oral surgeries, including complications due to dental implants 14,15 .…”

Section: Dear Mr Editormentioning

confidence: 99%