Facial Plastic and Reconstructive Surgery

Wu, Sheng; Genther, Dane J.; Ciolek, Peter J.; Prendes, Brandon; Hopkins, Brent; Ku, Johnson

doi:10.1007/978-3-319-18035-9

Cited by 3 publications

(4 citation statements)

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“…A few clinical studies have demonstrated that ASCs administered through intra-arterial and intramuscular injection could increase microvascular supply in patients with critical limb ischemia (27, 28). However, intra-arterial injection of SVF cells may induce microembolisms (14). Narrowing or blocking the lumen of terminal arterioles due to microembolism may result in no-flow in corresponding capillaries.…”

Section: Discussionmentioning

confidence: 99%

“…SVF cells, which could be obtained in large quantities without cell culture, contain heterogeneous cell populations, including stem cells and endothelial cells known to accelerate angiogenesis. Recently, beneficial effects of SVF cell injection on microcirculation have been reported in in vitro and in vivo studies (11–14). However, no clinical studies reported the effect of SVF cell injection on microcirculation in diabetic patients who commonly experience compromised tissue perfusion regardless of the status of the intravascular blood flow.…”

Section: Introductionmentioning

confidence: 99%

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Possibility of Injecting Adipose-Derived Stromal Vascular Fraction Cells to Accelerate Microcirculation in Ischemic Diabetic Feet: A Pilot Study

Moon

Chung

Han

et al. 2019

IJSC

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Background and Objectives Beneficial effects of human adipose-derived stromal vascular fraction (SVF) cell injection on microcirculation have been recently reported in in vitro and in vivo studies. However, no clinical studies have reported its effect in diabetic patients who commonly experience compromised tissue perfusion, regardless of the status of intravascular blood flow. The present piloting study was designed to clinically examine the possibility of SVF cell injection to accelerate microcirculation, particularly in ischemic diabetic feet. Methods Ten diabetic feet were included to receive subcutaneous injection of SVF cells around wounds. Transcutaneous partial oxygen pressure (TcPO 2 ) and cutaneous microvascular blood flow were measured before and every four weeks after cell injection until the 12 th week visit. Results TcPO 2 values increased from 31.3±7.4 before injection to 46.4±8.2 mmHg at 12 weeks after SVF injection (1.5-fold, p<0.05). Cutaneous microvascular blood flow levels increased from 34.0±21.1 before injection to 76.1±32.5 perfusion unit at 12 weeks after SVF injection (2.2-fold, p<0.05). There were no adverse events related to SVF cell injection. Conclusions Results of this study demonstrate that adipose-derived SVF cell injection have the possibility to provide beneficial effects on microcirculation in ischemic diabetic feet.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Possibility of Injecting Adipose-Derived Stromal Vascular Fraction Cells to Accelerate Microcirculation in Ischemic Diabetic Feet: A Pilot Study

Moon

Chung

Han

et al. 2019

IJSC

View full text Add to dashboard Cite

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“…Moisturization with a hydrophobic ointment during the initial stages of healing inhibits bacterial growth and promotes reepithelialization. 9 Silicone sheeting and gels can be utilized alone or in conjunction with other modalities (e.g. ointment) to improve the appearance of scars.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

“…ointment) to improve the appearance of scars. 9 The aim of this systematic review is to evaluate clinical evidence concerning the efficacy of EOs in wound/scar management.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Effects of Essential Oils on Scars and Wound Healing: A Systematic Review

et al. 2022

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BACKGROUND: Essential oils (EOs) have been considered as a potential alternative therapy for wound healing and scar reduction. OBJECTIVE: To provide a comprehensive review examining the effects of EOs on wound healing and scars. DATA SOURCES: PubMed, Cochrane, Ovid and Embase computerized searches were performed through June 2020. REVIEW METHODS: Two independent reviewers conducted data extraction reviewed by the senior author following the PRISMA protocol. RESULTS: Three manuscripts examining three different EO-containing topical agents were analyzed. Outcomes include: healing rate, erythema, pain, pruritus, patient discomfort, physician satisfaction, percent wound reduction, wound/scar surface perimeter area, and qualitative dermatological evaluation. All articles concluded that the EO-containing topical agents resulted in either superior or non-inferior outcomes in comparison to controls. Hypericum-Calendula oil obtained lower wound surface perimeter area. Erythema (p=.001) was significantly decreased by the peppermint EO-containing topical agent preparation. Physicians also reported greater satisfaction (p<.001) in wound appearance with use of the peppermint EO-containing topical agent. <b><u>CONCLUSION:</u></b> A paucity of studies have examined EO use for wound healing and scar reduction. Treatment with EO-containing topical agents resulted in decreased erythema with increased physician satisfaction of wound appearance. Future studies should assess what level of purity is needed for improved results, and which EO, or combination of EOs is most beneficial.

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Addressing the Upper Third of the Nose in Endonasal Rhinoplasty

Gupta

2021

Facial Plast Surg

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Effective management of the upper nasal vault is based on a thorough preoperative analysis and detailed understanding of the requisite principles and techniques utilized to modify the anatomic structures in this region. The surgeon must equally consider form and function when performing manipulation of the upper nasal vault. Special considerations apply when managing this anatomic region via an endonasal or closed approach. A review of this topic is presented with a focus on techniques as they apply to the endonasal rhinoplasty patient.

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Facial Plastic and Reconstructive Surgery

Cited by 3 publications

References 0 publications

Possibility of Injecting Adipose-Derived Stromal Vascular Fraction Cells to Accelerate Microcirculation in Ischemic Diabetic Feet: A Pilot Study

Possibility of Injecting Adipose-Derived Stromal Vascular Fraction Cells to Accelerate Microcirculation in Ischemic Diabetic Feet: A Pilot Study

Effects of Essential Oils on Scars and Wound Healing: A Systematic Review

Addressing the Upper Third of the Nose in Endonasal Rhinoplasty

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