Facial Emotion Labeling Deficits in Children and Adolescents at Risk for Bipolar Disorder

Systematic review of the neural basis of social cognition in patients with mood disorders

“…98 However, other studies have failed to find significant associations between levels of brain activation and mood state 92,94 or symptom severity in patients with bipolar disorder. 80,81,86,189 Illness burden A limited number of studies have examined the relation between burden of illness variables and neural activity during affective facial processing in patients with bipolar disorder. Recent work has demonstrated significant associations between an earlier illness onset and both amygdala hyperactivity 86 and decreased activity within the DLPFC.…”

Deficits in recognition, identification, and discrimination of facial emotions in patients with bipolar disorder

“…The ability to recognize emotion expressions was evaluated in both groups using the following three tasks: 1) the Facial Emotion Identification Test (FEIT) [8][9][10][11][12][13][14][15][16] shows 19 black and white pictures of six basic emotions (happy, sad, anger, surprise, disgust, and shame) which the participant must identify; 2) the Facial Emotion Discrimination Test (FEDT) [8][9][10][11][12][13][14][15][16] comprises 30 pairs of black and white pictures with faces presented concurrently. This test requires the participant to determine whether the two faces in each pair of pictures are displaying the same or different emotions; and 3) Emotion Recognition-40 (ER40).…”

“…This test requires the participant to determine whether the two faces in each pair of pictures are displaying the same or different emotions; and 3) Emotion Recognition-40 (ER40). [9][10][11][12][13][14][15][16][17] This test shows 40 pictures in which participants have to identify the displayed emotion. There are five options: anger, sad, fear, happy, and no emotion.…”

“…9 Several neuroimaging studies have explored the neural correlates of this trait deficit of emotion recognition in BD. [10][11][12][13] Despite some mixed findings, they overall propose an abnormally increased activity in subcortical and limbic emotion processing regions (e.g., the amygdala) and reduced responses in prefrontal cortical emotion regulation regions (see reviews).…”

Emotional and Motivational Processes in Bipolar Disorder: A Neural Network Perspective

“…On a behavioral level, relatives of bipolar disorder patients showed significant deficits in recognizing and labeling emotional faces correctly [201][202][203], yet no difference in emotional responsiveness operationalized by choosing the emotion that would best fit the description of a real-life situation was observed [203]. While rating their fear of fearful faces, unaffected subjects at-risk for bipolar disorder exhibited amygdala hyperactivity [204].…”