Facebook Experiences of Users With Traumatic Brain Injury: A Think-Aloud Study

Ahmadi, Reihaneh; Lim, Hajin; Mutlu, Bilge; Duff, Melissa C.; Toma, Catalina L.; Turkstra, Lyn S.

doi:10.2196/39984

Cited by 5 publications

(1 citation statement)

References 53 publications

(83 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition to pharmacological interventions, enriched environments with monitored exercise 107–109 and virtual environments are deemed helpful during chronic TBI recovery in rodents 110 and humans 111, 112 , including virtual social networks. 113 Future investigations, in addition to assessing influence of sex should investigate how vascular smooth muscle attributes are modified by TBI 114 and how pericytes regulate blood flow. 115 Finally, chronic TBI sequelae such as BBB dysfunction, TGFβ signaling, and neuroinflammation also contribute to the long-term sequelae injury.…”

Section: Discussionmentioning

confidence: 99%

Delayed cerebrovascular dysfunction and social deficits after traumatic brain injury

Singh,

Gong,

et al. 2024

Preprint

View full text Add to dashboard Cite

Traumatic brain injury (TBI) survivors face debilitating long-term psychosocial consequences, including social isolation and depression. Acute TBI modifies neurovascular physiology and behavior but a gap in our understanding are the chronic physiological implications of altered brain perfusion on behavioral activities, particularly social interactions.We investigated longitudinal functional vascular networks across the brain for 2-months post- TBI and its impact on social behavior. Adult C57/BL6 male mice received a moderate cortical TBI. Behavior (foot-fault, open-field, 3-chamber social preference) was assessed at baseline, 3-, 7-, 14-, 30-, and 60-days post injury (dpi) followed by magnetic resonance imaging (MRI, 9.4T). Anatomical MRI (T2-weighted), dynamic susceptibility contrast (DSC) perfusion weighted MRI (PWI) were acquired at each temporal epoch. After the final 60dpi MRI, animals underwent transcardial perfusion fixation to map angioarchitecture. MRI data were analyzed using standardized protocols followed by cross-correlations between social behavior, cerebral perfusion, and vascular metrics.Social behavior deficits at 60dpi emerged as reduced interaction with a familiar cage-mate (partner). We observed multiphasic decrements in cerebral blood flow (CBF) encompassing lesion and perilesional cortex where acute reductions at 3-14dpi partially recovered by 30dpi, followed by significant reductions in perfusion at 60dpi. The CBF perturbations extended antero-posteriorly from the ipsilateral TBI impact site but also adulterated contralateral brain regions. CBF reductions impacted regions known to regulate social behavior including hippocampus, hypothalamus, and rhinal cortex. Alongside perfusion deficits at 60dpi, social isolation in TBI-mice emerged with a significant decline in preference to spend time with a cage mate. Cortical vascular density was also reduced corroborating the decline in brain perfusion and social interaction.Thus, the novel temporal neurovascular loss, and subsequent recovery followed by chronic decrements are broadly reflected by social interaction perturbations. Our correlations strongly implicate a linkage between vascular density, cerebral perfusion, and social interactions, where early evaluation can potentially predict long-term outcomes. Thus, our study provides a clinically relevant timeline of alterations in functional vascular recovery that can guide research for future therapeutics.

show abstract

Section: Discussionmentioning

confidence: 99%

Delayed cerebrovascular dysfunction and social deficits after traumatic brain injury

Singh,

Gong,

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

How do Individuals With and Without Traumatic Brain Injury Interpret Emoji? Similarities and Differences in Perceived Valence, Arousal, and Emotion Representation

Clough,

Tanguay,

Mutlu

et al. 2023

J Nonverbal Behav

View full text Add to dashboard Cite

Impaired facial affect recognition is common after traumatic brain injury (TBI) and linked to poor social outcomes. We explored whether perception of emotions depicted by emoji is also impaired after TBI. Fifty participants with TBI and 50 non-injured peers generated free-text labels to describe emotions depicted by emoji and rated their levels of valence and arousal on nine-point rating scales. We compared how the two groups’ valence and arousal ratings were clustered and examined agreement in the words participants used to describe emoji. Hierarchical clustering of affect ratings produced four emoji clusters in the non-injured group and three emoji clusters in the TBI group. Whereas the non-injured group had a strongly positive and a moderately positive cluster, the TBI group had a single positive valence cluster, undifferentiated by arousal. Despite differences in cluster numbers, hierarchical structures of the two groups’ emoji ratings were significantly correlated. Most emoji had high agreement in the words participants with and without TBI used to describe them. Participants with TBI perceived emoji similarly to non-injured peers, used similar words to describe emoji, and rated emoji similarly on the valence dimension. Individuals with TBI showed small differences in perceived arousal for a minority of emoji. Overall, results suggest that basic recognition processes do not explain challenges in computer-mediated communication reported by adults with TBI. Examining perception of emoji in context by people with TBI is an essential next step for advancing our understanding of functional communication in computer-mediated contexts after brain injury.

show abstract

Use of Social Media Data Mining to Examine Needs, Concerns, and Experiences of People With Traumatic Brain Injury

Pei,

O'Brien

2024

Am J Speech Lang Pathol

View full text Add to dashboard Cite

Purpose: Given the limited availability of topic-specific resources, many people turn to anonymous social media platforms such as Reddit to seek information and connect to others with similar experiences and needs. Mining of such data can therefore identify unmet needs within the community and allow speech-language pathologists to incorporate clients' real-life insights into clinical practices. Method: A mixed-method analysis was performed on 3,648 traumatic brain injury (TBI) subreddit posts created between 2013 and 2021. Sentiment analysis was used to determine the sentiment expressed in each post; topic modeling and qualitative content analysis were used to uncover the main topics discussed across posts. Subgroup analyses were conducted based on injury severity, chronicity, and whether the post was authored by a person with TBI or a close other. Results: There was no significant difference between the number of posts with positive sentiment and the number of posts with negative sentiment. Comparisons between subgroups showed significantly higher positive sentiment in posts by or about people with moderate-to-severe TBI (compared to mild TBI) and who were more than 1 month postinjury (compared to less than 1 month). Posts by close others had significantly higher positive sentiment than posts by people with TBI. Topic modeling identified three meta-themes: Recovery, Symptoms, and Medical Care. Qualitative content analysis further revealed that returning to productivity and life as well as sharing recovery tips were the primary focus under the Recovery theme. Symptom-related posts often discussed symptom management and validation of experiences. The Medical Care theme encompassed concerns regarding diagnosis, medication, and treatment. Conclusions: Concerns and needs shift over time following TBI, and they extend beyond health and functioning to participation in meaningful daily activities. The findings can inform the development of tailored educational resources and rehabilitative approaches, facilitating recovery and community building for individuals with TBI. Supplemental Material: https://doi.org/10.23641/asha.24881340

show abstract

Facebook Experiences of Users With Traumatic Brain Injury: A Think-Aloud Study

Cited by 5 publications

References 53 publications

Delayed cerebrovascular dysfunction and social deficits after traumatic brain injury

Delayed cerebrovascular dysfunction and social deficits after traumatic brain injury

How do Individuals With and Without Traumatic Brain Injury Interpret Emoji? Similarities and Differences in Perceived Valence, Arousal, and Emotion Representation

Use of Social Media Data Mining to Examine Needs, Concerns, and Experiences of People With Traumatic Brain Injury

Contact Info

Product

Resources

About