Face Value: Challenges of Transplant Technology

Rg, Hartman

doi:10.1177/009885880503100101

Cited by 19 publications

(11 citation statements)

References 60 publications

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“…Additionally, the close association of these grafts with one's personal sense of identity and bodily integrity may lower willingness to donate for vascularized composite allotransplantation. 121,122,123 Depending on the general public's perception of self-inflicted injuries, it is possible that potential FT donors and their family members may object to the idea of donating tissues for transplantation in recipients with an SIGW, even if they are willing to donate for vascularized composite allotransplantation procedures overall. In solid organ transplantation, self-inflicted MOI draws mixed reactions from the public, with support dwindling in some, while in others it does not influence willingness to donate.…”

Section: Public Perception and Donor Considerationsmentioning

confidence: 99%

Self-Inflicted Gunshot Wound as a Consideration in the Patient Selection Process for Facial Transplantation

McQuinn¹,

Kimberly²,

Parent³

et al. 2019

Camb Q Healthc Ethics

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Abstract:Facial transplantation is emerging as a therapeutic option for self-inflicted gunshot wounds. The self-inflicted nature of this injury raises questions about the appropriate role of self-harm in determining patient eligibility. Potential candidates for facial transplantation undergo extensive psychosocial screening. The presence of a self-inflicted gunshot wound warrants special attention to ensure that a patient is prepared to undergo a demanding procedure that poses significant risk, as well as stringent lifelong management. Herein, we explore the ethics of considering mechanism of injury in the patient selection process, referring to the precedent set forth in solid organ transplantation. We also consider the available evidence regarding outcomes of individuals transplanted for self-inflicted mechanisms of injury in both solid organ and facial transplantation. We conclude that while the presence of a self-inflicted gunshot wound is significant in the overall evaluation of the candidate, it does not on its own warrant exclusion from consideration for a facial transplantation.

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Section: Public Perception and Donor Considerationsmentioning

confidence: 99%

Self-Inflicted Gunshot Wound as a Consideration in the Patient Selection Process for Facial Transplantation

McQuinn¹,

Kimberly²,

Parent³

et al. 2019

Camb Q Healthc Ethics

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“…This imagery could unknowingly affect the CFHT donation process when requesting donation. 32 For CFHT, the donor procurement process may present some additional problems never-before considered. For instance, Qayumi et al found that greater than 2 hours of ischemia can predispose allografts to increased rates of graft rejection.…”

Section: Donor-related Considerationsmentioning

confidence: 99%

Concomitant Face and Hand Transplantation

Gordon¹,

Zor²,

Cetrulo³

et al. 2011

Annals of Plastic Surgery

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Face and hand composite tissue allotransplantations have evolved into a promising subset of reconstructive transplant surgery due to recent advances in immunotherapy. Concomitant composite tissue allotransplantation, which involves a variable combination of facial (myocutaneous versus osteomyocutaneous) and upper extremity (ie, various levels) composite subtypes, has been performed infrequently at this time. In this review, we will describe many reasons as to why this field remains unexplored. Undoubtedly, future investigation is warranted to investigate the potential advantages and disadvantages of using this approach versus a staged manner for alloreconstruction and to identify the complexities of cortical reorganization and rehabilitation in this setting.

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“…The recipients will look neither like themselves nor like the donor: instead they will have a composite identity. 41 The effects of this on different people will be different. 42 43 Indeed, the effects on men and women may be different, although no evidence exists that the gender question has been investigated.…”

Section: P 8)mentioning

confidence: 99%

“…Does it not pose a threat to human dignity? 41 Nor do we know how others will react to the recipient of a face transplant. The recipients' family, friends and acquaintances may not recognise in them the person they knew and loved before the transplant took place.…”

Section: P 254)mentioning

confidence: 99%