Face–Name Associative Memory Performance Among Cognitively Healthy Individuals, Individuals With Subjective Memory Complaints, and Patients With a Diagnosis of aMCI

Kormas, Constantinos; Zalonis, Ioannis; Evdokimidis, Ioannis; Kapaki, Elisabeth; Potagas, Constantin

doi:10.3389/fpsyg.2020.02173

Cited by 10 publications

(20 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In those tasks, the lower performance level of the participants with SCD was not attributable to differences among the groups in terms of education level or depressive symptoms. These results are in line with studies indicating that tasks with a high cognitive processing load may be helpful for detecting impairment in SCD [ 20 , 23 , 24 , 25 , 26 , 27 , 50 , 51 ].…”

Section: Discussionsupporting

confidence: 91%

“…A similar relationship between SCD and delayed recall in verbal episodic memory was reported in a sample of individuals with a few depressive symptoms [ 22 ]. Furthermore, a decline in performance in tests exploring associative memory, memory binding, prospective memory, and visual short-term memory has been found in individuals with SCD [ 23 , 24 , 25 , 26 , 27 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Use of Executive Fluency Tasks to Detect Cognitive Impairment in Individuals with Subjective Cognitive Decline

Macoir

Tremblay

Hudon

2022

Behavioral Sciences

View full text Add to dashboard Cite

Objective: Although evidence has indicated that subjective cognitive decline (SCD) may be an early sign of Alzheimer’s disease (AD), the objectification of cognitive impairment in SCD is challenging, mainly due to the lack of sensitivity in assessment tools. The present study investigated the potential contribution of two verbal fluency tasks with high executive processing loads to the identification of cognitive impairment in SCD. Methods: A total of 60 adults with SCD and 60 healthy controls (HCs) performed one free action (verb) fluency task and two fluency tasks with more executive processing load—an alternating fluency task and an orthographic constraint fluency task—and the results were compared. Result: In the free action fluency task, the performance of the participants with SCD and the HCs was similar. However, HCs performed significantly better than SCD in the alternating fluency task, which required mental flexibility, and the orthographic constraint fluency task, which required inhibition. Discussion: The study findings suggest that verbal fluency tasks with high executive processing load could be useful in detecting cognitive deficits at the preclinical stage of AD. The inclusion of such tests in assessment batteries should be considered in order to improve the detection of subtle cognitive impairment in preclinical major neurocognitive disorder populations.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

The Use of Executive Fluency Tasks to Detect Cognitive Impairment in Individuals with Subjective Cognitive Decline

Macoir

Tremblay

Hudon

2022

Behavioral Sciences

View full text Add to dashboard Cite

show abstract

“…In the present study, SCD participants were recruited by looking for older adults with memory complaints in nonclinical settings. In the study by Kormas et al (2020); however, SCD participants were recruited from a memory clinic, in which participants sought cognitive consultation. The This document is copyrighted by the American Psychological Association or one of its allied publishers.…”

Section: Tablementioning

confidence: 99%

“…FNAME performance in aMCI subjects has been found to be worse than clinically normal older adults and is correlated with other measures of episodic and semantic memory Papp et al, 2014). In a recent study, SCD subjects also displayed worse performance than older adult controls with normal performance on cognitive testing without memory complaints (CON) in FNAME delayed recall, which was even more affected in aMCI subjects (Kormas et al, 2020), which is consistent with a previous study using a face-name recognition computerized task (Polcher et al, 2017). Furthermore, FNAME performance correlates with β-amyloid and tau protein cerebrospinal fluid biomarkers (indicative of AD pathology) and cortical volumetric measurements in the right This document is copyrighted by the American Psychological Association or one of its allied publishers.…”

mentioning

confidence: 97%

Extended FNAME performance is preserved in subjective cognitive decline but highly affected in amnestic mild cognitive impairment.

Flores-Vázquez¹,

Contreras-López²,

Stegeman³

et al. 2023

Neuropsychology

View full text Add to dashboard Cite

Objective: The cognitive characterization of Alzheimer’s disease risk states, such as amnestic mild cognitive impairment (aMCI) and subjective cognitive decline (SCD), is fundamental for timely diagnosis and interventions. The Face Name Associative Memory Exam (FNAME) is sensitive to early Alzheimer’s disease brain changes, and an extended version captures a fuller range of associative memory abilities. We aimed to assess group effects in the extended FNAME in older adults with SCD, aMCI, and older adult controls (CON). Method: Two concurrently created versions of the extended FNAME were used to test three groups of older adults (CON = 35, SCD = 37, aMCI = 31) at two sites (Mexico = 59, Netherlands = 44). Extended FNAME memory abilities were analyzed in five analyses of variance. Group and site were considered as independent variables. For the recall ability, subtest levels were entered as a within-subject variable. The remaining abilities (Face Recognition, Name Recognition, Spontaneous Name Recall, and Face–Name Matching) were analyzed in independent models. Results: In all models, the main effect for group was significant with large effect sizes, driven by a worse performance of aMCI participants. No significant differences were found between SCD and CON. The main effect for site was only significant in Face Recognition. Conclusions: The worse performance of aMCI in the extended FNAME implies an impairment in associative memory abilities beyond recall. The similar performance of CON and SCD might be explained by the recruitment of SCD participants that did not spontaneously seek help for memory decline.

show abstract

“…Unfortunately, AM is affected by different neurological states and conditions-it declines with normal ageing [5], and its impairment has been identified as one of the early and prominent symptoms of mild cognitive impairment (MCI) and dementia [6,7]. The AM tests have been even proposed as assessment and diagnostic tools for MCI and Alzheimer's disease [8,9]. Due to generally weak response of memory deficits to pharmacological treatment [10,11], interest in development and application of different non-invasive brain stimulation (NIBS) techniques and protocols to promote AM, ultimately aiming at NIBS treatments for memory deficits [12][13][14], has sparked.…”

Section: Introductionmentioning

confidence: 99%

Personalized Frequency Modulated Transcranial Electrical Stimulation for Associative Memory Enhancement

et al. 2022

View full text Add to dashboard Cite

Associative memory (AM) is the ability to remember the relationship between previously unrelated items. AM is significantly affected by normal aging and neurodegenerative conditions, thus there is a growing interest in applying non-invasive brain stimulation (NIBS) techniques for AM enhancement. A growing body of studies identifies posterior parietal cortex (PPC) as the most promising cortical target for both transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES) to modulate a cortico-hippocampal network that underlines AM. In that sense, theta frequency oscillatory tES protocols, targeted towards the hallmark oscillatory activity within the cortico-hippocampal network, are increasingly coming to prominence. To increase precision and effectiveness, the need for EEG guided individualization of the tES protocols is proposed. Here, we present the study protocol in which two types of personalized oscillatory tES–transcranial alternating current stimulation (tACS) and oscillatory transcranial direct current stimulation (otDCS), both frequency-modulated to the individual theta-band frequency (ITF), are compared to the non-oscillatory transcranial direct current stimulation (tDCS) and to the sham stimulation. The study has cross-over design with four tES conditions (tACS, otDCS, tDCS, sham), and the comprehensive set of neurophysiological (resting state EEG and AM-evoked EEG) and behavioral outcomes, including AM tasks (short-term associative memory, face–word, face–object, object-location), as well as measures of other cognitive functions (cognitive control, verbal fluency, and working memory).

show abstract

Face–Name Associative Memory Performance Among Cognitively Healthy Individuals, Individuals With Subjective Memory Complaints, and Patients With a Diagnosis of aMCI

Cited by 10 publications

References 78 publications

The Use of Executive Fluency Tasks to Detect Cognitive Impairment in Individuals with Subjective Cognitive Decline

The Use of Executive Fluency Tasks to Detect Cognitive Impairment in Individuals with Subjective Cognitive Decline

Extended FNAME performance is preserved in subjective cognitive decline but highly affected in amnestic mild cognitive impairment.

Personalized Frequency Modulated Transcranial Electrical Stimulation for Associative Memory Enhancement

Contact Info

Product

Resources

About