2020
DOI: 10.1016/j.molliq.2020.113024
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Fabrication of temperature and pH sensitive decorated magnetic nanoparticles as effective biosensors for targeted delivery of acyclovir anti-cancer drug

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Cited by 46 publications
(10 citation statements)
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“…Previous works have proposed MNCs with pH-sensitive properties, expanding the utilization of this material for diagnostic and therapeutic applications. For instance, Wu et al fabricated nickel–gold bimetallic nanoparticles enwrapped by a pH-responsive copolymer gel . They found that a change in the hydrodynamic radius of this MNC by varying the pH value directly correlated with the fluorescent signal and response time under a magnetic field.…”
Section: Resultsmentioning
confidence: 99%
“…Previous works have proposed MNCs with pH-sensitive properties, expanding the utilization of this material for diagnostic and therapeutic applications. For instance, Wu et al fabricated nickel–gold bimetallic nanoparticles enwrapped by a pH-responsive copolymer gel . They found that a change in the hydrodynamic radius of this MNC by varying the pH value directly correlated with the fluorescent signal and response time under a magnetic field.…”
Section: Resultsmentioning
confidence: 99%
“…Targeted delivery of drugs by functionalized magnetic nanoparticles is particularly worth investigating in anticancer treatment [ 20 , 21 ]. Xie et al conducted studies on the fabrication of magnetic nanoparticles as carriers of acyclovir—the active substance known for its anticancer activity [ 22 ]. Next, Saepudin et al reported on various substances used for the modification of magnetic nanoparticles to achieve the effective release of doxorubicin by such formed drug carriers [ 23 ].…”
Section: Introductionmentioning
confidence: 99%
“…Inorganic nanocarriers with high mechanical strength and good chemical stability are widely applied in the drug delivery systems to control the drug release in the target tissue. [15][16][17][18][19][20] Few studies have been published that explain the coordination properties of Cetz mixed metal complexes which behaves as monodentate ligand in the deprotonated mode with Co(II), Ni(II), and Cu(II) through the moiety of carboxylic acid. [21][22][23][24][25] As a bidentate organic molecule metal-binding field, Bipy (Scheme 1b) is still used as a scaffold in macromolecular and metallosupramolecular structures.…”
Section: Introductionmentioning
confidence: 99%