Fabrication of rod-like nanocapsules based on polylactide and 3,4-dihydroxyphenylalanine for a drug delivery system

Shi, Dongjian; Zhang, Lei; Jiali, Shen; Li, Xiaojie; Chen, Mingqing; Akashi, Mitsuru

doi:10.1039/c5ra21549h

Cited by 11 publications

(13 citation statements)

References 32 publications

(33 reference statements)

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“…Dopamine (DA) is a derivative of 3,4‐dihydroxyphenethylamine (DOPA), which is from the mussel adhesive protein . DA is reported to show high adhesive property on various materials, due to its strong interactions with other materials via chemical and physical interactions.…”

Section: Introductionmentioning

confidence: 99%

“…Dopamine (DA) is a derivative of 3,4-dihydroxyphenethylamine (DOPA), which is from the mussel adhesive protein. [18][19][20][21] DA is reported to show high adhesive property on various materials, due to its strong interactions with other materials via chemical and physical interactions. Moreover, DA can be oxidized to form o-quinone, and then o-quinone can self-polymerize to form polydopamine (PDA) in a weak alkaline buffer solution.…”

Section: Introductionmentioning

confidence: 99%

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Fabrication of polydopamine nanoparticles knotted alginate scaffolds and their properties

Jiali

Shi

Dong

et al. 2018

J Biomedical Materials Res

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Polydopamine (PDA) can greatly affect polymer's properties, due to the chemical and physical interactions between the polymers and PDA. In this study, PDA was demonstrated to adjust the pore structures and increase the mechanical properties of alginate hydrogel‐based cartilage tissue scaffolds. Dopamine modified alginate (Alg‐DA) was firstly synthesized by modification of Alg with DA. Alg‐DA interacted with preprepared PDA nanoparticles and further crosslinked with calcium ions (Ca2+) to form the hydrogel scaffold (Alg‐DA/PDA). The Alg‐DA/PDA scaffold combined multiple advantageous features, including continuous pore structure, high level of porosity, well mechanical properties, good biocompatibility and appropriate cycle life of degradation. Moreover, it could provide an optimized forming environment for hydroxyapatite (HAp) by mineralization process, thus accelerating cartilage repair. The improved performances were mainly ascribed to physical enhancement of the PDA nanoparticles and crosslinking points among the polymers and catechol groups in DA. These findings might offer a guideline for fabricating robust biocompatible cartilage tissue scaffold. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 3255–3266, 2018.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fabrication of polydopamine nanoparticles knotted alginate scaffolds and their properties

Jiali

Shi

Dong

et al. 2018

J Biomedical Materials Res

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“…Templates have also been used to alter the morphology of polycatecholamines, such as the imprinting of small molecules and proteins mentioned in the previous section. Materials such as polymers, silica, zinc oxide, and curcumin have also been used as templates, with subsequent removal of the template, resulting in the fabrication of hollow polydopamine spheres and nanotubes . An interesting example of template directed synthesis is the formation of capped, coiled fibers through dopamine polymerization in the presence of lipid nanotubes.…”

Section: Catecholamine Polymers: Chemistry and Structurementioning

confidence: 99%

“…Polycatecholamines have found significant use in drug delivery for a number of purposes, such as in the construction of capsules, nanotubes, and colloidosomes to provide internal cavities suitable for drug loading and subsequent release. Further, polydopamine coatings on both organic and inorganic nanoparticles containing drugs have enhanced stability and controlled release of internalized active ingredients . This includes pH, near‐infrared, and redox chemistry mediated release of drugs .…”

Section: Applications Of Catecholamine Polymersmentioning

confidence: 99%

“…Further, polydopamine coatings on both organic and inorganic nanoparticles containing drugs have enhanced stability and controlled release of internalized active ingredients . This includes pH, near‐infrared, and redox chemistry mediated release of drugs . Related polydopamine coatings have also been used to functionalize the drug containing nanoparticles with both stealth coatings to reduce clearance from body and with ligands to target delivery …”

Section: Applications Of Catecholamine Polymersmentioning

confidence: 99%

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Versatile Surface Modification Using Polydopamine and Related Polycatecholamines: Chemistry, Structure, and Applications

Barclay

Hegab

Clarke

et al. 2017

Adv Materials Inter

291

223

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Almost ten years ago, Lee et al. [13] formulated a universal adhesive coating based on observation of the strong attachment by mussels through their byssal threads to virtually all types of inorganic and organic surfaces. The amino acid compositions of the mussel foot proteins that generate the attachment are rich in catechol and amine groups. [13][14][15] These groups associate under marine conditions, forming strong covalent and noncovalent interactions with substrates. [13] This led to the idea that both catechol and amine groups were crucial in forming robust, wide spectrum adhesive nanolayers [16,17] and consequently dopamine was conceived as a powerful building block for spontaneous deposition of thin polymer films. The dopamine monomer is deposited onto unadulterated surfaces through self-assembly and oxidative cross-linking from mild pH aqueous solution in a rapid reaction. This results in a durable, nanoscale, conformal, and hydrophilic coating that can be readily modified to introduce specific surface chemistries for a particular application. [18][19][20][21][22] These bioinspired, polydopamine materials are chemically and structurally indistinguishable from eumelanins found in the human body, [23,24] providing excellent biocompatibility. Additionally, polydopamine has broad electromagnetic absorption and excellent photothermal energy conversion [25] as well as having ionic-electronic hybrid conductivity. [26] Along with the excellent coating performance, these properties provide a vast array of potential applications for polydopamine materials.In this article, we explain what is known about polydopamine and related catecholamine coatings; their formation, the adhesion mechanism, and their physicochemical properties and we also review the applications of these materials (Figure 1). Since 2011, there have been a number of reviews on this subject matter, including general reviews on the physicochemical properties of polydopamine coatings [11,20,[27][28][29] and their applications. [20,27,30] There are also a number of more specific reviews on the chemical synthesis and modulation of polycatecholamine coatings, [31] the biomedical applications of these coatings, [8,[32][33][34] their electronic properties, [26,35] the use of polydopamine to make films at fluid interfaces, [36] in hierarchically constructed particles, [33] and capsules, [30] exploitation of polycatecholamine coatings in membrane filtration, [37] polydopamine-derived carbon materials, [38] and the use of coordination chemistry in catechol-based materials. [39] Nonetheless, this area of research is growing so rapidly [25,27] that many recent Polydopamine and related polycatecholamines can be easily deposited onto almost any surface from mild, aqueous solution. This results in durable, nanoscale coatings that exhibit high biocompatibility and have useful chemical and electronic properties. Additionally, these materials can be readily chemically and physically modified, and consequently, they are used extensively for surface modification. This ...

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Polydopamine‐Incorporated Nanoformulations for Biomedical Applications

Zheng

Ding

Gao

2020

Macromolecular Bioscience

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Polydopamine (PDA), a pigment in natural melanin, has attracted considerable attention because of its excellent optical properties, extraordinary adhesion, and good biocompatibility, which make it a promising material for application in energy, environmental, and biomedical fields. In this review, PDA‐incorporated nanoformulations are focused for biomedical applications such as drug delivery, bioimaging, and tumor therapy. First, the recent advances in PDA‐incorporated nanoformulations for drug delivery are discussed. Further, their application in boimaging, such as fluorescence imaging, photothermal imaging, and photoacoustic imaging, is reviewed. Next, their therapeutic applications, including chemotherapy, photodynamic therapy, photothermal therapy, and synergistic therapy are discussed. Finally, other biomedical applications of PDA‐incorporated nanoformulations such as biosensing and clinical diagnosis are briefly presented. Finally, the biomedical applications of PDA‐incorporated nanoformulations along with their prospects are summarized.

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Fabrication of rod-like nanocapsules based on polylactide and 3,4-dihydroxyphenylalanine for a drug delivery system

Abstract: Rod-like nanocapsules were facilely fabricated based on a bio-based polymer via DOPA adhesion. The nanocapsules showed high drug-loading efficacies and controlled drug release depending on different pH buffer solutions.

Cited by 11 publications

References 32 publications

Fabrication of polydopamine nanoparticles knotted alginate scaffolds and their properties

Fabrication of polydopamine nanoparticles knotted alginate scaffolds and their properties

Versatile Surface Modification Using Polydopamine and Related Polycatecholamines: Chemistry, Structure, and Applications

Polydopamine‐Incorporated Nanoformulations for Biomedical Applications

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