Fabrication of Protein-Conjugated Silver Sulfide Nanorods in the Bovine Serum Albumin Solution

Abstract

Highly ordered silver sulfide nanorods conjugated with the Bovine Serum Albumin (BSA) protein have been successfully achieved at ambient temperature. Such a process is very simple and controllable, directly using silver nitrate and thioacetamide (TAA) as the reactants in the aqueous solution of BSA. The products have been characterized by XRD, HRTEM-SAED, SEM-EDS, TG-DTA, FT-IR, and CD spectroscopy. The results of the research show that the as-prepared Ag2S nanorods are monodispersed with sizes about 40 nm in diameter and 220 nm in length, and exhibit a high degree of crystallinity and good photoluminescence. Furthermore, an interesting mechanism is discussed for the formation of the Ag2S nanorods.

Submucosal injection of the silver–human albumin complex for the treatment of bronchopleural fistula

“…The mixed product obtained in this way is unstable since it would require additional reactant for stable fixation. However, this instability provides some advantages after the submucosal injection, allowing a gradual release of silver nitrate in the surrounding tissue [13,14]. This phenomenon maintains the silver nitrate in the tissue for a longer time, favouring a stronger and permanent local effect.…”

Fungus-mediated biological synthesis of gold nanoparticles: potential in detection of liver cancer

“…23,24 The unique optical and electronic properties of gold nanoparticles make them ideal candidates for cell targeting and also as efficient tools for bioassays. 25 On this basis, we sought to develop a fluorescence-based biosensor using liver cancer cell surface-specific (LCCS) antibody-conjugated gold colloids to probe cancer cells specifically in a mixed cell population.…”

Facile synthesis and functionalization of water-soluble gold nanoparticles for a bioprobe

“…Several studies on the bioconjugation of nanoparticles have been reported in the recent years [28][29][30][31][32]. Jose-Yacaman and co-workers reported the synthesis of gold nanoparticles directly conjugated to BSA by chemical reduction in aqueous solution [29].…”

“…Jose-Yacaman and co-workers reported the synthesis of gold nanoparticles directly conjugated to BSA by chemical reduction in aqueous solution [29]. In another study, highly ordered silver sulfide nanorods conjugated with BSA have been successfully achieved [30]. Using -potential and quartz crystal microbalance measurements, Brewer et al showed that the conjugation of BSA with gold nanoparticles occurred mostly by an electrostatic mechanism [31].…”