Fabrication of Multscale Fractal-Like Structures by Controlling Fluid Interface Instability

Islam, Tanveer ul; Gandhi, Prasanna S.

doi:10.1038/srep37187

Cited by 35 publications

(20 citation statements)

References 48 publications

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“…These approaches do not lend themselves to producing individual tags that can be read by cell phone but the micro-dendrites could be used as taggant agents in goods and materials, much like coded nanostructures [82]. Finally, there is also the possibility of using the Saffman-Taylor instability, also described earlier, to make large-scale coarse dendrites in a 'lifted Hele-Shaw cell apparatus', in which a viscous fluid is pressed between two plates that are separated at one edge to allow the influx of air which results in a ramified viscous fingering effect [83][84][85].…”

Section: Discussionmentioning

confidence: 95%

Information in electrodeposited dendrites

Kozicki

2021

Advances in Physics: X

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Dendrites are structures that develop with a continuously branching tree-like form. Such patterns are found in many aspects of the natural world, which indicates the universality of their topology. This review presents an examination of dendritic structures, addressing their stochasticity and fractal character, and exploring their information content or more specifically their ability to provide a very large number of unique patterns that may be used as a novel form of item identification. A brief summary of fractals and their dimensionality is presented and applied to the well-known diffusion limited aggregate (DLA) dendritic construct. Dendrites formed by electrochemical 'self-assembly' are explored and examples given of their formation under different conditions. Stochastic variations in the self-similar Y-shaped symbol that underlies these fractals can carry information, leading to significant entropy, even though the structural entropy of the overall pattern is relatively small.

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Section: Discussionmentioning

confidence: 95%

Information in electrodeposited dendrites

Kozicki

2021

Advances in Physics: X

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“…Diameter of source-holes in the present study is kept equal to 0.5 mm for all the experiments. Locations of these holes were based on the guidelines given in (Islam and Gandhi 2016) such that we would evolve a square mesh structure after the process is done. The square mesh with several sizes and pitch dimensions are proposed to be prepared.…”

Section: Controlling Source-holesmentioning

confidence: 99%

Scalable large-area mesh-structured microfluidic gradient generator for drug testing applications

Yadav

Tawade

Bachal

et al. 2022

Preprint

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The present work aims to develop a microfluidic device from a square mesh template. The template is fabricated using a recently proposed non conventional lithographyless method of shaping ceramic suspension fluid by controlling Saffman Taylor instability in a Multiport Lifted Hele-Shaw Cell (MLHSC). The microfluidic concentration gradient generator (μCGG) was prepared by soft lithography from fabricated template. The optimum flow rates were determined by COMSOL simulations and validated by creating fluorescein dye (Fluorescein isothiocanate, FITC) gradient in the fabricated μCGG. We then demonstrated the use of this device for drug testing. We created various concentration of an anticancer drug, curcumin, using the device and then determined inhibitory concentration of curcumin on the viability of cervical cancer cell line (HeLa). The result matched well with the conventional drug testing using 96 well plates. Further, shaping of fluid allows change in the number of outlets, which can be utilised to achieve broad range of concentration gradient. Therefore, this method is time efficient, cost effective, uniquely suitable to scale microstructures over a large area, and saves personnel time and can be used as a gradient generator for various biological and non biological applications.

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“…The fabrication process of the LMM is shown in Figure 2 (a). The fractal microchannel network was obtained using a bespoke Hele-Shaw apparatus based on Saffman-Taylor instabilities [22]. A thoroughly mixed ceramic suspension was used to create the mold for the fractal channel network [23].…”

Section: A Device Fabricationmentioning

confidence: 99%

Insight into the Design and Fabrication of a Leaf-Mimicking Micropump

et al. 2019

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A micropump is the heart of any microfluidic device that finds applications in several lab-on-chip devices. Passive micropumps are highly desirable for this purpose due to their ease of integration, low energy requirements and simplistic design and operation. The design of a plant leaf serves as a natural inspiration for developing an evaporation assisted passive micropump. The presence of branching channel like venation pattern ensures water distribution to the spongy mesophyll cells increasing the surface area for evaporation. However, due to its multiscale design and complexity of the venation pattern, emulating a leaf's design is challenging. Apart from the lack of understanding of design parameters that affect fluid flow, manufacturing limitations impede the development of such bio-inspired micropumps. Inspired by the multi-scale design of the leaf, in this work we propose a passive micropump mimicking the structure of a leaf. Employing evaporation and capillary pressure as the pumping mechanism, our leaf mimicking micropump consists of a microporous membrane integrated with a branched, fractal channel network resembling a leaf's venation pattern. Our proposed fabrication methodology is simple, scalable, inexpensive and uses readily available materials. We demonstrate a significant increase in the fluid flow rate due to the addition of this branched channel network. We support our experimental observations using an analytical model, wherein we discuss the design parameters that affect the pumping rate. Correspondingly, the performance of these micropumps can be optimized based on intrinsic and extrinsic factors as per the desired applications.

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Fabrication of Multscale Fractal-Like Structures by Controlling Fluid Interface Instability

Cited by 35 publications

References 48 publications

Information in electrodeposited dendrites

Information in electrodeposited dendrites

Scalable large-area mesh-structured microfluidic gradient generator for drug testing applications

Insight into the Design and Fabrication of a Leaf-Mimicking Micropump

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