Fabrication of Janus-type nanocomposites from cellulose nanocrystals for self-healing hydrogels’ flexible sensors

Janus hydrogels: merging boundaries in tissue engineering for enhanced biomaterials and regenerative therapies

“…They have undergone vigorous development, evolving from initial microscale nanomaterials 21 to various macroscopic forms such as membranes 22 and hydrogels. 23 New methods for controlling the size, shape, microstructure, and chemical properties of Janus materials have emerged, including template methods, 24 selfassembly techniques, 25 and microfluidic approaches, 26 to meet specific application requirements. Despite the significant advances in research on Janus hydrogels, which are hydrogel materials consisting of a "Janus" structure, the number of publications on the use of Janus hydrogels in tissue engineering and regenerative medicine to solve real-world problems is still relatively limited compared to the ongoing development of other materials.…”

Janus structure hydrogels: recent advances in synthetic strategies, biomedical microstructure and (bio)applications

“…JNPs generally display two contradictory yet non-conflicting traits concurrently when compared to other constructions. JNPs, with their diverse nanomaterial combinations, are highly suitable for a vast array of uses, including but not limited to sensors, 10,11 soft actuators, [12][13][14] drug delivery, 15,16 and seawater desalination. [17][18][19] As an example, Xiaojin Zhang and colleagues created tough Janus adhesive hydrogels by producing gold nanoparticles (AuNPs) within a gelatin-polyacrylamide (GA) double network hydrogel.…”