Fabrication of In Situ‐Cross‐Linked N‐Succinyl Chitosan/Oxidized Alginate Hydrogel‐Loaded Ascorbic Acid and Biphasic Calcium Phosphate for Bone Tissue Engineering
Thanh‐Thuong Le Duong,
Binh Thanh Vu,
Hanh Thi‐Kieu Ta
et al.
Abstract:Bone tissue engineering is a promising technology being studied globally to become an effective and sustainable method to treat the problems of damaged or diseased bones. In this work, we developed an in situ cross‐linking hydrogel system that combined N‐succinyl chitosan (NSC) and oxidized alginate (OA) at varying mixing ratios through Schiff base cross‐linking. The hydrogel system also contains biphasic calcium phosphate (BCP) and ascorbic acid (AA), which could enhance biological characteristics and acceler… Show more
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