Fabrication of Hybrid Polymeric Micelles Containing AuNPs and Metalloporphyrin in the Core

Abstract

Multi-structure assemblies consisting of gold nanoparticles and porphyrin were fabricated by using diblock copolymer, poly(ethylene glycol)-block-poly(4-vinylpyridine) (PEG-b-P4VP). The copolymer of PEG-b-P4VP was used in the formation of core-shell micelles in water, in which the P4VP block serves as the core, while the PEG block forms the shell. In the micellar core, gold nanoparticle and metalloporphyrin were dispersed through the axial coordination. Structural and morphological characterizations of the complex micelle were carried out by transmission electron microscopy, laser light scatting, and UV-visible spectroscopy. Metalloporphyrin in the complex micelle exhibited excellent photostability by reducing the generation of the singlet oxygen. This strategy may provide a novel approach to design photocatalysts that have target applications in photocatalysis and solar cells.

Modulation of Intratumoral Fusobacterium nucleatum to Enhance Sonodynamic Therapy for Colorectal Cancer with Reduced Phototoxic Skin Injury

“…Porphyrins generally cause severe phototoxicity in the skin when exposed to light, which hinders their clinical application. − Au NPs are superior electron/energy receivers, which could convert the excited singlet state of porphyrins through electron/energy transfer, thereby reducing the formation of the triplet state of porphyrins. − Energy/electron transfer may occur from CuPpIX to Au NPs under light conditions, which could reduce the ROS production excited by light to prevent porphyrins from damaging the skin. Therefore, engineered Au@BSA-CuPpIX may weaken and even eliminate the phototoxicity of porphyrins to protect skin from damage.…”

Structure/Property Control in Photocatalytic Organic Semiconductor Nanocrystals

“…Thanks to these features, the complex showed excellent photocatalytic activity in reducing methyl viologen (MV 2+ ). [ 114 ] When Pd QDs were incorporated into PDI/TiO 2 NPs via hydrothermal reduction, in addition to electron transfer from PDI to Pd QDs, Pd QDs resembled Au NPs in the SPR enhanced absorption or the back‐electron transfer from plasmonic Pd QDs to PDI. [ 115 ] The back‐electron transfer was revealed by the enhanced photoelectrical conversion efficiency and the back‐electron reduction of PDI into PDI radical anions.…”

Micellization of a starch–poly(1,4-butylene succinate) nano-hybrid for enhanced energy storage

“…28,29 The switching of the conformations of these micellar nano-architectures can therefore be used to tune the conductance, capacitance, energy and power densities of supercapacitor electrodes for the storage of electrical charges. [28][29][30] For example, this method is applied in conductive electrophoretic image displays, electrorheological uids, and ink jet imprintings. [29][30][31][32] Therefore, the aim of this particular work is to primarily use a green method to specically design different sustainable micellar nano-architectures based on poly(1,4-butylene succinate) cores, and uncarbonized starch heads with impregnated nano-magnetite.…”

“…[28][29][30] For example, this method is applied in conductive electrophoretic image displays, electrorheological uids, and ink jet imprintings. [29][30][31][32] Therefore, the aim of this particular work is to primarily use a green method to specically design different sustainable micellar nano-architectures based on poly(1,4-butylene succinate) cores, and uncarbonized starch heads with impregnated nano-magnetite. The effect of each micellar design on the overall electrochemical conductivity and capacitive performance of starch-PBS nanohybrids will be studied.…”