Fabrication of Chitosan Nanoparticles Containing Samarium IonPotentially Applicable for Fluorescence Detection and Energy Transfer

Usman, Anwar; Kusrini, Eny; Widiantoro, Andikaputra Brahma; Hardiya, Esza; Abdullah, Nurul Aliah; Yulizar, Yoki

doi:10.14716/ijtech.v9i6.2576

Cited by 14 publications

(15 citation statements)

References 14 publications

(22 reference statements)

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“…CHN apparently exhibited a flake-like layered structure with variable sizes. Similar observations have been reported by Kusrini et al (2015b) and Usman et al (2018) for commercially sourced CHN, exhibiting irregular blocks with a size of 1−100 μm. Meanwhile, the synthetic HAP surface was porous and thinly twisted similar to a nest-like structure.…”

Section: Morphology and Composition Studiessupporting

confidence: 88%

Micro-structured Materials for the Removal of Heavy Metals using a Natural Polymer Composite

Kusrini¹,

Ayuningtyas²,

Mawarni³

et al. 2021

IJTech

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In this study, a precipitation method was employed to prepare a synthetic hydroxyapatite (HAP)/chitosan (CHN) composite by the modification of synthetic HAP with CHN. The HAP/CHN composite was characterized by Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy equipped with energy-dispersive X-ray spectroscopy (SEM-EDX). Furthermore, the HAP/CHN composite in a 1:1 ratio (wt.%) was investigated as an adsorbent for the removal of heavy metals ions (such as Cr 6+ , Cd 2+ and Zn 2+ ) from simulated wastewater. Adsorption experiments were conducted in batch mode at room temperature. In addition, the effect of process conditions, such as contact time, was evaluated. Kinetic data were well-described by the pseudo-second-order kinetic model, where adsorption was governed by the intraparticle diffusion model. The HAP/CHN composite demonstrated potential utility as an adsorbent for the removal of heavy metals from an aqueous solution, with the highest maximum adsorption capacities of 39.3, 30.8 and 29.9 mg/g for Cr 6+ , Cd 2+ and Zn 2+ , respectively. The HAP/CHN composite materials with variable structure and composition exhibited remarkably different adsorption properties and potential applicability for industrial applications due to the material cost-effectiveness.

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Section: Morphology and Composition Studiessupporting

confidence: 88%

Micro-structured Materials for the Removal of Heavy Metals using a Natural Polymer Composite

Kusrini¹,

Ayuningtyas²,

Mawarni³

et al. 2021

IJTech

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“…With reference to a similar method, the microwave technique has been found to be effective in degrading larger molecules into smaller compounds (Usman et al, 2018). A low-power microwave apparatus was used to drive the bond breaking of chitosan into nanoparticles with different sizes (317 nm).…”

Section: Uv260 and Docmentioning

confidence: 99%

Enhancement of Drinking Water Treatment by Combined Filtration-ICPS: Integrated, Based on EEMS, DOC, UV260 and Removal of Pathogenic Bacteria

Desmiarti¹,

Hazmi²,

Trianda³

et al. 2019

IJTech

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The impact of natural organic matter (NOM) and pathogenic bacteria in water are of great concern in water treatment due to their effect on human health. In this study, the ability to combine filtration with an inductively coupled plasma system (ICPS) to remove natural organic matter and pathogenic bacteria from water was investigated. UV260 adsorption, dissolved organic carbon (DOC) and excitation-emission matrices (EEMs) were used to evaluate the removal of NOM by the filtration-ICPS combination. The system was operated at two different flow rates, 100 and 150 ml/minute. Decreasing trend revealed for UV260 and DOC with the higher flow rate. Tryptophan-like substances generally found in water were taken as a measure of microbial activity. This preliminary research shows that the average removal efficiencies for fecal coliforms, total coliforms and salmonella were highest at a flow rate of 100 ml/minute. It can be concluded that the combined filtration-ICPS method is capable of removing NOM and pathogenic bacteria from water.

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“…(18C6)) complex has been proven to show antiamoebic activity against Acanthamoeba sp. (Kusrini et al 2016), and acyclic and cyclic samarium complexes such as [Sm(Pic) 2 (EO5)](Pic), [Sm(Pic) 2 (18C6)](Pic) (Kusrini et al 2018) and Sm‐chitosan (Usman et al 2018) have been known as an active luminescence centre due to the 4f‐4f localized trap‐creating ion. The complexes of the rare earth elements (REEs) as anti‐bacterial agents have better efficiencies compared to their salts (Moradi et al 2017; Ami Hazlin et al 2018).…”

Section: Introductionmentioning

confidence: 99%

Design, synthesis and antiamoebic activity of dysprosium‐based nanoparticles using contact lenses as carriers against Acanthamoeba sp.

Kusrini

Sabira

Hashim

et al. 2020

Acta Ophthalmologica

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Purpose Contact lenses have direct contact with the corneal surface and can induce sight‐threatening infection of the cornea known as Acanthamoeba keratitis. The objective of this study was to evaluate the dysprosium‐based nanoparticles (Dy‐based NPs), namely Fe3O4‐PEG‐Dy2O3 nanocomposites and Dy(OH)3 nanorods, as an active component against Acanthamoeba sp., as well as the possibility of their loading onto contact lenses as the drug administering vehicle to treat Acanthamoeba keratitis (AK). Methods The Dy‐based NPs were synthesized, and they were loaded onto commercial contact lenses. The loading content of the NPs and their release kinetics was determined based on the absorbance of their colloidal solution before and after soaking the contact lenses. The cytotoxicity of the NPs was evaluated, and the IC50 values of their antiamoebic activity against Acanthamoeba sp. were determined by MTT colorimetric assay, followed by observation on the morphological changes by using light microscopy. The mechanism of action of the Dy‐based NPs against Acanthamoeba sp. was evaluated by DNA laddering assays. Results The loading efficiencies of the Dy‐based NPs onto the contact lens were in the range of 30.6–36.1% with respect to their initial concentration (0.5 mg ml–1). The Dy NPs were released with the flux approximately 5.5–11 μg cm–2 hr–1, and the release was completed within 10 hr. The emission of the NPs consistently showed a peak at 575 nm due to Dy3+ ion, offering the possible monitoring and tracking of the NPs. The SEM images indicated the NPs are aggregated on the surface of the contact lenses. The DNA ladder assay suggested that the cells underwent DNA fragmentation, and the cell death was due most probably to necrosis, rather than apoptosis. The cytotoxicity assay of Acanthamoeba sp. suggested that Fe3O4‐PEG, Fe3O4‐PEG‐Dy2O3, Dy(NO3)3.6H2O and Dy(OH)3 NPs have an antiamoebic activity with the IC50 value being 4.5, 5.0, 9.5 and 22.5 μg ml–1, respectively. Conclusions Overall findings in this study suggested that the Dy‐based NPs can be considered as active antiamoebic agents and possess the potential as drugs against Acanthamoeba sp. The NPs could be loaded onto the contact lenses; thus, they can be potentially utilized to treat Acanthamoeba keratitis (AK).

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Fabrication of Chitosan Nanoparticles Containing Samarium IonPotentially Applicable for Fluorescence Detection and Energy Transfer

Cited by 14 publications

References 14 publications

Micro-structured Materials for the Removal of Heavy Metals using a Natural Polymer Composite

Micro-structured Materials for the Removal of Heavy Metals using a Natural Polymer Composite

Enhancement of Drinking Water Treatment by Combined Filtration-ICPS: Integrated, Based on EEMS, DOC, UV260 and Removal of Pathogenic Bacteria

Design, synthesis and antiamoebic activity of dysprosium‐based nanoparticles using contact lenses as carriers against Acanthamoeba sp.

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