Fabrication of an Impedimetric Immunosensor for Screening and Determination of Vincristine in Biological Samples

Nabiabad, Haidar Saify; Amini, Massoumeh

doi:10.1134/s1061934820080092

Cited by 3 publications

(4 citation statements)

References 24 publications

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“…The comparison of analytical efficacy between as-fabricated electrode and other non-electrochemical and electrochemical methods was performed for Vincristine ( Table 1 ) ( Yong et al, 2004 ; Gupta et al, 2005 ; Babkina and Ulakhovich, 2011 ; Zhang et al, 2016b ; Amila Jeewantha et al, 2017 ; Kiani et al, 2018 ; Saify Nabiabad and Amini, 2020 ; Jin et al, 2021 ). Based on Table 1 , the detection limit and linear range of as-fabricated sensor were better than those of non-electrochemical methods ( Gupta et al, 2005 ; Amila Jeewantha et al, 2017 ; Kiani et al, 2018 ; Jin et al, 2021 ).…”

Section: Resultsmentioning

confidence: 99%

“…In addition, the performance of our proposed DNA biosensor for sensing Vincristine displayed a comparable linear range and better detection limit and sensitivity when comparing with the other electrochemical methods. The detection limit of only Ref ( Saify Nabiabad and Amini, 2020 ). developed for detection of Vincristine was superior to our sensor.…”

Section: Resultsmentioning

confidence: 99%

“…developed for detection of Vincristine was superior to our sensor. The strength of our work than Ref (Saify Nabiabad and Amini, 2020). was the use of nondestructive, non-toxic and cost-effective modifiers (ds-DNA/PP/ P-L CuO:Tb 3+ NS) when comparing with Au nanoparticles, carbon nanotubes, monoclonal antibody.…”

Section: Comparison Of Proposed Biosensor With Other Reported Analyti...mentioning

confidence: 93%

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Development of the DNA-based voltammetric biosensor for detection of vincristine as anticancer drug

et al. 2023

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In the article presented herein, a deoxyribonucleic acid (DNA) biosensor is introduced for Vincristine determination in pharmaceutical preparations based on the modification of screen printed electrode (SPE) with double-stranded DNA (ds-DNA), polypyrrole (PP), peony-like CuO:Tb3+ nanostructure (P-L CuO:Tb3+ NS). The developed sensor indicated a wide linear response to Vincristine concentration ranged from 1.0 nM to 400.0 μM with a limit of detection as low as .21 nM. The intercalation of Vincristine with DNA guanine led to the response. The optimized parameters for the biosensor performance were ds-DNA/Vincristine interaction time, DNA concentration and type of buffer solution. The docking investigation confirm the minor groove interaction between guanine base at surface of or ds-DNA/PP/P-L CuO:Tb3+ NS/SPE and Vincristine. The proposed sensor could successfully determine Vincristine in Vincristine injections and biological fluids, with acceptable obtains.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Comparison Of Proposed Biosensor With Other Reported Analyti...mentioning

confidence: 93%

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Development of the DNA-based voltammetric biosensor for detection of vincristine as anticancer drug

et al. 2023

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“…Solvent bar micro-extraction combined with high-pressure liquid chromatography was used for pre-concentration and determination of trace amounts of VCR in body fluids such as plasma and urine [16]. The application of an electrochemical biosensor for the determination of VCR in human serum samples was also reported [17].…”

Section: Introductionmentioning

confidence: 99%

The Development of New Methodology for Determination of Vincristine (VCR) in Human Serum Using LC-MS/MS-Based Method for Medical Diagnostics

Jurowski

Paprotny²,

Zakrzewski³

et al. 2022

Molecules

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In this article, we have presented the development and validation of a rapid and sensitive reversed-phase liquid chromatography with tandem mass spectrometry (LC-MS/MS) method for the determination of vincristine (VCR) in patient serum samples. Chromatographic separation was achieved on a Kinetex® (Singapore) column using a mobile phase consisting of 25 mM acetic acid and 0.3% formic acid (A) and methanol (B) in a gradient elution mode at a flow rate of 0.3 mL/min. The VCR and internal standard (vinblastine) were monitored using the multiple reaction monitoring mode under positive electrospray ionization. The lower limit of quantification (LLOQ) was 0.67 ng/mL, and the upper limit of quantification (ULOQ) was 250 ng/mL for VCR. The calculated values of LOD and LOQ for VCR were 0.075 and 0.228 ng/mL, respectively. The calibration curve was linear over the VCR concentration range of 1.0–250 ng/mL in serum. The intra- and inter-day precision and precision were within the generally accepted criteria for the bioanalytical method (<15%). The method was successfully applied to the analysis of serum samples in clinical practice.

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(Bio)electroanalysis of microtubule-targeting agents used in cancer chemotherapy

Popa

David

Cheregi

et al. 2023

Microchemical Journal

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Fabrication of an Impedimetric Immunosensor for Screening and Determination of Vincristine in Biological Samples

Cited by 3 publications

References 24 publications

Development of the DNA-based voltammetric biosensor for detection of vincristine as anticancer drug

Development of the DNA-based voltammetric biosensor for detection of vincristine as anticancer drug

The Development of New Methodology for Determination of Vincristine (VCR) in Human Serum Using LC-MS/MS-Based Method for Medical Diagnostics

(Bio)electroanalysis of microtubule-targeting agents used in cancer chemotherapy

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