Fabrication of a Novel Cholic Acid Modified OPE-Based Fluorescent Film and Its Sensing Performances to Inorganic Acids in Acetone

Cui, Hairong; He, Gang; Wang, Hongyue; Sun, Xiaohuan; Liu, Taihong; Ding, Liping; Fang, Yu

doi:10.1021/am302069p

Cited by 14 publications

(21 citation statements)

References 38 publications

(42 reference statements)

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“…211 Generally, the sensing of the SAM film with the one-molecule-thick layer occurs in a short response time. 213 The introduction of cholic acid (CholA) into the side-chains of OPE prevented the aggregation of the OPE backbones and improved the solubility in organic media, promoting the covalent attachment of CholA-OPE to the silane layers on the surface of the substrate. In this section, the current progress on the luminescent film based on the SAM technique is presented.…”

Section: Luminescent Films Via the Selfassembled Monolayer (Sam) Methodsmentioning

confidence: 99%

Luminescent films for chemo- and biosensing

et al. 2015

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Luminescent films have received great interest for chemo-/bio-sensing applications due to their distinct advantages over solution-based probes, such as good stability and portability, tunable shape and size, non-invasion, real-time detection, extensive suitability in gas/vapor sensing, and recycling. On the other hand, they can achieve selective and sensitive detection of chemical/biological species using special luminophores with a recognition moiety or the assembly of common luminophores and functional materials. Nowadays, the extensively used assembly techniques include drop-casting/spin-coating, Langmuir-Blodgett (LB), self-assembled monolayers (SAMs), layer-by-layer (LBL), and electrospinning. Therefore, this review summarizes the recent advances in luminescent films with these assembly techniques and their applications in chemo-/bio-sensing. We mainly focused on the discussion of the relationship between the sensing properties of the films and their architecture. Furthermore, we discussed some critical challenges existing in this field and possible solutions that have been or are being developed to overcome these challenges.

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Section: Luminescent Films Via the Selfassembled Monolayer (Sam) Methodsmentioning

confidence: 99%

Luminescent films for chemo- and biosensing

et al. 2015

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“…A large excess of 1,8-dibromooctane was used to prevent two-fold reaction on one alkyl chain and potassium carbonate was found to give better yields than sodium hydroxide 16 or sodium hydride (in ethanol). Both monomers (5 and 7) needed for the Sonogashira polymerization reaction were synthesized via similar pathways (Scheme 2).…”

Section: Resultsmentioning

confidence: 99%

Synthesis of a multifunctional poly(p-phenylene ethynylene) scaffold with clickable azide-containing side chains for (bio)sensor applications

et al. 2015

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Poly(p-phenylene ethynylene) (PPE) copolymers with alternating alkoxy and azide-functionalized alkoxy side chains were efficiently synthesized via Sonogashira polymerization and the materials were fully characterized. Among the different synthetic protocols investigated, the best results were obtained when employing a pre-polymerization functionalization approach and upon implementing the azide-functionalized side chains on the diiodophenyl building block. End-capping of the conjugated polymer chains is shown to be essential for preventing side reactions. As a proof of principle, phenylacetylene is clicked in a nearly quantitative way on the polymer backbone. Furthermore, successful click-immobilization of randomly alkynylated protein A onto an azide-functionalized PPE film illustrates the potential use of these materials in a variety of (bio)sensor applications. † Electronic supplementary information (ESI) available: MALDI-TOF mass spectrum of copolymer P2a, 1 H and 13 C NMR spectra of monomers and polymers, cyclic voltammograms, and FT-IR spectra. See

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“…1, right part). [43][44][45] Unlike the construction of SA-2D films based on a low-molecular-mass fluorophore, the creation of novel SA-2D films based on a conjugated polymer or oligomer is hard to achieve via simply varying the linker structures, which is one of the most commonly adopted strategies in the creation of films with novel structures and properties. It is believed that most of the sensing sites are exposed in the monolayer film and are easily reached by the analyte.…”

Section: Conventional Fluorescent Sensing Filmsmentioning

confidence: 99%

“…(Fig. 44 It was demonstrated that the two CholA moieties that were attached to the side chains of the fluorophore not only affected the fluorescence behavior of the film, but also favored the formation of hydrophilic pockets above the BPEB adlayer when the film was exposed to acetone. Fluorescence and molecular dynamics modeling studies revealed that the long, flexible alkyl chains played a crucial role in the smart sensing performance of the oligomer-based film.…”

Section: Conventional Fluorescent Sensing Filmsmentioning

confidence: 99%

Recent advances in fluorescent film sensing from the perspective of both molecular design and film engineering

Miao

Peng

Fang

2016

Mol. Syst. Des. Eng.

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Fluorescence is now a dominant technology and is used extensively in many fields owing to its incomparable properties. On account of its advantages, scientists and engineers have been investigating novel and powerful fluorescent sensors and sensor arrays for real-life applications, in which the construction of highperformance fluorescent films plays a prominent role. The appropriate immobilization of suitable fluorescent sensing elements onto a given substrate is an efficient way to construct usable fluorescent films. Molecular design and film fabrication are two key issues in the development of films because they determine the sensing performance of the films. Via the careful design and selection of sensing fluorophores, the development of convenient film fabrication strategies and the study of the relevant sensing dynamics, a variety of fluorescent sensing films with desirable sensing performance have been developed over at least the last ten years. This review describes recent progress in this important area of science, which combines surface and interface chemistry, photophysics and materials science.High-performance sensing films are the key to real-life usable fluorescent sensors. Different strategies have been developed to fabricate fluorescent sensing films during the previous decades, which mainly include physical coating, doping, single-layer chemistry and molecular gel-based fabrication. The asdeveloped films can be divided into disordered and generally densely packed physical films, 2-dimensional chemical films and 3-dimensional networked physical films. To enhance sensing performance, the structures of films should be optimized both at a molecular level and on a microscopic scale. Therefore, more factors are involved in the design of sensing molecules; in particular, some functional structures need to be introduced to obtain films with favorable adlayer structures. A molecular gel strategy possesses advantages in the fabrication of fluorescent sensing films: 1) increased surface density and effectiveness of sensing sites; 2) increased speed and reversibility of response; and 3) ease of scale-up. However, this strategy is still open to improvement. For example, a general method is urgently needed to increase the adhesive and mechanical strength of gel-based films. Films that were fabricated using the newly developed strategy have found important applications in the sensitive and fast detection of hidden explosives and illegal drugs.

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Fabrication of a Novel Cholic Acid Modified OPE-Based Fluorescent Film and Its Sensing Performances to Inorganic Acids in Acetone

Cited by 14 publications

References 38 publications

Luminescent films for chemo- and biosensing

Luminescent films for chemo- and biosensing

Synthesis of a multifunctional poly(p-phenylene ethynylene) scaffold with clickable azide-containing side chains for (bio)sensor applications

Recent advances in fluorescent film sensing from the perspective of both molecular design and film engineering

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