Fabrication of a new electrochemical sensor based on screen-printed carbon electrode/amine-functionalized graphene oxide-Cu nanoparticles for Rohypnol direct determination in drink sample

Mohammadnia, Maryam Saleh; Naghian, Ebrahim; Ghalkhani, Masoumeh; Nosratzehi, Fatemeh; Adib, Kourosh; Zahedi, Mir Mahdi; Nasrabadi, Mehdi Rahimi; Ahmadi, Farhad

doi:10.1016/j.jelechem.2020.114764

Cited by 24 publications

(10 citation statements)

References 39 publications

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“…Functionalized with amines, acids, enzymes, aptamers, or other biomolecules, SWCNTs are a great scaffold for biosensors, although these covalent modifications can be very complex and difficult to execute . Other disadvantages of SWCNTs stem from their strong van der Waals interactions, causing aggregations and imperfections that result in disrupted polymer matrices and nonuniform thin layers . Due to these insurmountable flaws of SWCNTs, they tend to be pushed aside for modern graphene materials and multiwalled carbon nanotubes, although SWCNTs mark an essential stepping stone to these more modern breakthroughs.…”

Section: Resultsmentioning

confidence: 99%

Materials Approaches for Improving Electrochemical Sensor Performance

Beaver

Dantanarayana

2021

J. Phys. Chem. B

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Electrochemical sensors have emerged as important diagnostic tools in recent years, due to their simplicity and ease of use. Compared to instrumental analysis methods that use complicated experimental and data analysis techniquessuch as mass spectrometry, nuclear magnetic resonance (NMR), spectrophotometric methods, and chromatography electrochemical sensors show promise for use in a wide range of real-time and in situ applications such as pharmaceutical testing, environmental monitoring, and medical diagnostics. In order to identify analytes in complex and/or biological samples, materials used for both the electrode materials and the chemically selective layer have been evolving throughout the years for optimizing the analytical performance of electrochemical sensors to increase sensitivity, selectivity and linear range. In this Perspective, attention will be focused on different types of materials that have been used for electrochemical sensing, including new combinations of well-studied materials as well as novel strategies to enhance the performance of sensing devices. The Perspective will also discuss existing challenges in the field and future strategies for addressing those challenges.

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Section: Resultsmentioning

confidence: 99%

Materials Approaches for Improving Electrochemical Sensor Performance

Beaver

Dantanarayana

2021

J. Phys. Chem. B

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“…2019 hybrid electrocatalyst modified SPCE was developed for the determination of flunitrazepam [ 111 ]; Lab-on-a-screen-printed electrochemical cell for drop-volume voltammetric screening and detection of flunitrazepam to a wide range of untreated and undiluted spiked samples (Pepsi cola (R), Vodka, Whisky, Tequila, Gin, and Rum) [ 112 ]; 2020 electrochemical sensor for on-site detection of flunitrazepam in spirits [ 113 ]; electrochemical sensor for trace analysis of flunitrazepam in aqueous solutions [ 114 ]; 2021 carbon paste electrode for electrochemical determination of flunitrazepam [ 115 ]; electrochemical sensor for detection of Rohypnol/flunitrazepam in drinks [ 116 ]; miniaturized sensing device for the determination of flunitrazepam in carbonated soft drinks, energy drink, and malt beverage [ 117 ]…”

Section: Routine and Improved Analyses Of Abused Substancesmentioning

confidence: 99%

Interpol Review of Drug Analysis 2019-2022

Love

Jones

2023

Forensic Science International: Synergy

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“…It was demonstrated for the first time that direct drop volume detection can detect FLU in a variety of different acidities (pH 2.3–8.4), untreated alcoholic beverages and soft drinks. Moreover, Mohammadnia and colleagues optimized SPGE electrodes via the preparation of positively charged amide‐functionalized GO nanosheets and copper nanoparticle (AGO‐Cu) composite modifications [130] . Due to the π‐bonding and easy oxidation characteristics in the FLU structure, the SPGE/AGO‐Cu composite electrode with large surface area and active copper sites was able to generate stronger electrical signals, improve the sensing performance, and enhance the sensitivity and stability with a LOD of 0.13 μM.…”

Section: Detection Strategy Of Flumentioning

confidence: 99%

Detection of Flunitrazepam in Biological Fluids and Beverages:A Review

Chen,

Huang,

Qiu

et al. 2023

ChemistrySelect

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Flunitrazepam, a very potent benzodiazepine with sedative, hypnotic and amnesic effects, is commonly used to treat severe insomnia and as an anesthetic. Due to these characteristics, when flunitrazepam is sneaked into alcohol or drinks, it is often highly associated with violent behavior and drug rape cases. Therefore, it is also known as a “date rape drug”, and the detection of flunitrazepam and its metabolites is of great interest in forensic medicine and pharmacotoxicology. This paper describes the mechanism of action and drug metabolism process of flunitrazepam, reviews the different methods for detecting flunitrazepam published over the years, summarizes the detection limits of each method and compares their advantages and disadvantages. We hope to provide some inspiration for future research in this field.

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Fabrication of a new electrochemical sensor based on screen-printed carbon electrode/amine-functionalized graphene oxide-Cu nanoparticles for Rohypnol direct determination in drink sample

Cited by 24 publications

References 39 publications

Materials Approaches for Improving Electrochemical Sensor Performance

Materials Approaches for Improving Electrochemical Sensor Performance

Interpol Review of Drug Analysis 2019-2022

Detection of Flunitrazepam in Biological Fluids and Beverages:A Review

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