Fabrication and Packaging of a Dual Sensing Electrochemical Biotransducer for Glucose and Lactate Useful in Intramuscular Physiologic Status Monitoring

Portable Bio-Devices: Design of electrochemical instruments from miniaturized to implantable devices

“…Nowadays, there is an increasing interest in the field of glucose biosensors, looking for Glucose Continous Monitoring (GCM). In the last years several works have been published in the field like Patel et al, (2007), where it's presented an electro-enzymatic glucose sensor, (Xi Huang et al, 2009), where it is introduced a capacitive based MEMS affinity sensor for continuous glucose monitoring applications, (Teymoori, Mir Majid et al, 2009) introducing a MEMS for glucose and other generical sensors in medical applications and (Rodrigues et al, 2007) where it's developed a new cell-based biochip dedicated to the real-time monitoring of transient effluxes of glucose and oxygen, using arrays of amperometric microsensors integrated in the inlet and the outlet of a PDMS cell chamber, and complete designs like (Rahman et al, 2009) where is presented the design, microfabrication, packaging, surface functionalization and in vitro testing of a complete electrochemical cell-on-a-chip (ECC) for the continuous amperometric monitoring of glucose, performing cyclic voltammetry, electrical impedance spectroscopy (EIS), and microscopic examination. Special interest has the development of nanosensors applied in this field.…”

Challenges facing academic research in commercializing event-detector implantable devices for an in-vivo biomedical subcutaneous device for biomedical analysis

“…Other interesting studies are provided by Rodrigues et al [45], who developed a new cell-based biochip dedicated to the real-time monitoring of transient effluxes of glucose and oxygen, using arrays of amperometric microsensors integrated in the inlet and the outlet of a PDMS cell chamber. A complete design is provided by Rahman et al [46], who present the design, microfabrication, packaging, surface functionalization and in vitro testing of a complete electrochemical cell-on-a-chip (ECC) for the continuous amperometric monitoring of glucose, performing cyclic voltammetry, electrical impedance spectroscopy (EIS) and microscopic examination.…”

New Perspectives in Biosensors Technology and Applications

“…Nowadays, there is an increasing interest in the field of glucose biosensors, looking for Glucose Continous Monitoring (GCM). In the last years several works have been published in the field like Patel et al, (2007), where it's presented an electro-enzymatic glucose sensor, (Xi Huang et al, 2009), where it is introduced a capacitive based MEMS affinity sensor for continuous glucose monitoring applications, (Teymoori, Mir Majid et al, 2009) introducing a MEMS for glucose and other generical sensors in medical applications and (Rodrigues et al, 2007) where it's developed a new cell-based biochip dedicated to the real-time monitoring of transient effluxes of glucose and oxygen, using arrays of amperometric microsensors integrated in the inlet and the outlet of a PDMS cell chamber, and complete designs like (Rahman et al, 2009) where is presented the design, microfabrication, packaging, surface functionalization and in vitro testing of a complete electrochemical cell-on-a-chip (ECC) for the continuous amperometric monitoring of glucose, performing cyclic voltammetry, electrical impedance spectroscopy (EIS), and microscopic examination. Special interest has the development of nanosensors applied in this field.…”