Fabrication and evaluation of carboxymethylated diethylaminoethyl cellulose microcarriers as support for cellular applications

Recent Developments of Carboxymethyl Cellulose

“…are highly facilitated when microcarrier surfaces are modified with various anionic or cationic species instead of the neat-cellulose carriers. Recently, Ramezani Kalmer and his co-workers (2019) [242] synthesized a carboxymethylated multifunctional water-soluble cellulosic microcarrier (average diameter 1650 ± 100 µm, size 1500-1800 µm) from diethylamonioethyl cellulose (DEAEC) with the contemporaneous presence of anionic and cationic functional groups. The CMC/DEAEC carriers demonstrated themselves as a high-performance supporting biomaterial for cell adhesion, immobilization, and proliferation.…”

Assuring the Safety of Cultivated Meat: HACCP plan development and application to a cultivated meat target-product

“…Typically, a HACCP team would develop the flow diagram and perform an on-site review of the operation to validate its accuracy and completeness, but as this is a case study based on a theoretical product, the study team built the flow diagram using available scientific data describing methodologies and steps used in cultivated meat production (Bomkamp et al, 2022;Bodiu et al, 2020;Bradley, 1978;Brasil, 2004;Brasil, 2015b;USHHS, 2022;Ding et al, 2018;Rodríguez Escobar et al, 2021;Geraghty et al, 2014;USHHS, 2010;Hanga et al, 2020;Hanga et al, 2021;USHHS, 2009;Humbird, 2021;Ianovici et al, 2022;Joo et al, 2022;Kang et al, 2021;Kern et al, 2016;Inamdar et al, 2012;Flecknell, 2009;Letti et al, 2021;Li et al, 2021;Pereira;Oliveira, 2020;Post et al, 2020;Marga et al, 2015;Melzener et al, 2021;Melzener et al, 2022;Messmer et al, 2022;Ramezani et al, 2019;Sart;Agathos, 2016;Shit;Shah, 2014;Skrivergaard et al, 2021;Ben-Arye et al, 2020;Verbruggen et al, 2018;Genovese, 2017). The experts' previous experience establishing bioprocesses was also valuable to this outlining.…”

A Novel Nanofiber Hydrogel Adhesive Based on Carboxymethyl Cellulose Modified by Adenine and Thymine

“…Carboxymethyl cellulose is a commercially mature chemical product. This anionic cellulose water-soluble derivative has a wide range of applications [12,13] in food [14], textiles [15,16], pharmaceutical engineering [17], biomedical engineering [18], energy storage [19], and other fields due to its unique surface properties, biological adaptability, adjustable hydrophilicity, low cost, and abundant raw material sources. Due to its abundant hydroxyl groups, CMC can serve as a hydrogen bonding site, and its anionic polyelectrolyte properties can provide long-range electrostatic interactions, providing reliable cohesion and adhesion for CMC as an adhesive [20][21][22][23].…”