Fabrication and characterization of remineralizing dental composites containing calcium type pre-reacted glass-ionomer (PRG-Ca) fillers

Maia, Juliana Nunes da Silva Meirelles Dória; Portela, Maristela Barbosa; Candela, Dalber R.S.; Neves, Aline de Almeida; Noronha-Filho, Jaime Dutra; Mendes, Amanda de Oliveira; Barros, Mariana Araújo; Silva, Eduardo Moreira da

doi:10.1016/j.dental.2021.04.004

Cited by 9 publications

(4 citation statements)

References 62 publications

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“…First, the absence of the statistical influence of the water immersion protocol on water sorption and solubility can be seen as a desirable aspect by dental scientists because it suggests that the specimens do not need to be vertically positioned in water inside the vial, which is somewhat difficult to perform. Second, the statistical similarity of water sorption and solubility among the specimens with different sizes might represent an economical use of resin-based restorative materials for specimen building, especially when researchers are testing or developing new resin-based materials composed of special and expensive substances [ 76 ]. Although this study added interesting aspects regarding the protocol used to evaluate the water sorption and solubility of resin-based restorative materials, limitations such as the use of only distilled water as a storage medium and the absence of long-term evaluation still exist.…”

Section: Discussionmentioning

confidence: 99%

Influence of Specimen Dimension, Water Immersion Protocol, and Surface Roughness on Water Sorption and Solubility of Resin-Based Restorative Materials

da Silva,

Amaral,

Jardim

et al. 2024

Materials

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The evaluation of water sorption and solubility is pivotal for the development of new resin-based restorative materials with the potential for clinical application. The purpose of the present study was to evaluate the influence of the specimen dimension, water immersion protocol, and surface roughness on the water sorption and solubility of three resin-based restorative materials. Disk-shaped specimens of 15 mm × 1 mm, 10 mm × 1 mm, and 6 mm × 1 mm were produced with a composite resin (Z100), a resin cement (RelyX ARC), and an adhesive system (Single Bond 2—SB2). The specimens were immersed in distilled water according to four protocols: ISO (all the specimens for each group were vertically immersed in 50 mL); IV-10 (the specimens were individually and vertically immersed in 10 mL); IH-10 (the specimens were individually and horizontally immersed in 10 mL); and IH-2 (the specimens were individually and horizontally immersed in 2 mL). The surface roughness (Sa and Sp) was evaluated using an atomic force microscope, and the degree of conversion was determined using FT-IR spectrometry. The specimen dimension and water immersion protocol had no effect on water sorption and solubility. For the three resin-based restorative materials, Sp was higher than Sa. The degree of conversion was not influenced by the specimen dimension. The variations in the specimen dimension and water immersion protocol compared to those determined by ISO 4049 did not prevent the comparison between the values of water sorption and solubility obtained for a given resin-based restorative material.

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Section: Discussionmentioning

confidence: 99%

Influence of Specimen Dimension, Water Immersion Protocol, and Surface Roughness on Water Sorption and Solubility of Resin-Based Restorative Materials

da Silva,

Amaral,

Jardim

et al. 2024

Materials

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“…Integrating components with photoactivity and remineralization properties into the classical dental resin Bis-GMA/TEGDMA formulation is an effective strategy for improving the remineralization property of dental restorative resin. Former studies usually realized the mineralization of Bis-GMA/TEGDMA dental resin by incorporating fillers or coatings with a remineralization ability to the resin formulation [9,55,56]. In this study, a bifunctional monomer called CMA, which is the calcium salt of methacrylic acid, was incorporated into the Bis-GMA/TEGDMA dental resin formulation to develop a bioactive dental restorative resin.…”

Section: Discussionmentioning

confidence: 99%

Restorative Dental Resin Functionalized with Calcium Methacrylate with a Hydroxyapatite Remineralization Capacity

Zhang,

et al. 2023

Materials

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The ability of dental materials to induce the mineralization of enamel like hydroxyapatite (HA) is of great importance. In this article, a novel kind of dental restorative material characterized by a mineralization ability was fabricated by photopolymerization. Calcium methacrylate (CMA) was introduced into the classical bisphenol A-glycidyl methacrylate (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) dental resin formulation. This functional dental resin (BTCM) was calcium-rich and can be prepared simply by one-step photopolymerization. The influence of CMA on the photopolymerization kinetics, the dental resin’s mechanical properties, and its capacity to induce dynamic in situ HA mineralization were examined. Real-time FTIR, compression modulus, scanning electron microscopy, X-ray spectroscopy, MTT assay, and cell attachment test were carried out. The obtained data were analyzed for statistical significance using analysis of variance (ANOVA). Double bond conversion could be completed in less than 300 s, while the compression modulus of BTCM decreased with the increase in CMA content (30 wt%, 40 wt%, and 50 wt%). After being soaked in Ca(NO3)2 and Na2HPO4 solutions alternatively, dense HA crystals were found on the surface of the dental resin which contained CMA. The amount of HA increased with the increase in CMA content. The MTT results indicated that BTCM possesses good biocompatibility, while the cell adhesion and proliferation investigation demonstrated that L929 cells can adhere and proliferate well on the surface of BTM. Thus, our approach provides a straightforward, cost-effective, and environmentally friendly solution that has the potential for immediate clinical use.

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“…To augment the remineralization ability of BAG, Juliana et al infused different concentrations of calcium fluoride into a pre-reacted glass ionomer (PRG) [29]. The average diameter of PRG was found to be 4.89 µm.…”

Section: Bioactive Glassmentioning

confidence: 99%

Engineered Biomaterials Trigger Remineralization and Antimicrobial Effects for Dental Caries Restoration

Li,

Liu,

Xue

et al. 2023

Molecules

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Dental caries is the most prevalent chronic disease globally, significantly impacting individuals’ quality of life. A key reason behind the failure of implanted restorations is their biological inactivity, meaning they are unable to form crosslinks with the surrounding tooth structures, thus making patients susceptible to implant loss and recurrent tooth decay. For the treatment of caries, antibacterial medicine and remineralization are effective means of treating the recurrence of caries. Owing to the rapid progression in the biomaterials field, several biomaterials have been reported to display antimicrobial properties and aid in dentin remineralization. Bioactive materials hold considerable potential in diminishing biofilm accumulation, inhibiting the process of demineralization, enabling dentin remineralization, and combating bacteria related to caries. Bioactive materials, such as fluoride, amorphous calcium phosphate, bioactive glass, collagen, and resin-based materials, have demonstrated their effectiveness in promoting dentin remineralization and exerting antibacterial effects on dental caries. However, the concentration of fluoride needs to be strictly controlled. Although amorphous calcium phosphate can provide the necessary calcium and phosphorus ions for remineralization, it falls short in delivering the mechanical strength required for oral mastication. Resin-based materials also offer different advantages due to the complexity of their design. In this review, we delve into the application of advanced bioactive materials for enhancing dentin remineralization and antibacterial properties. We eagerly anticipate future developments in bioactive materials for the treatment of dental caries.

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Fabrication and characterization of remineralizing dental composites containing calcium type pre-reacted glass-ionomer (PRG-Ca) fillers

Cited by 9 publications

References 62 publications

Influence of Specimen Dimension, Water Immersion Protocol, and Surface Roughness on Water Sorption and Solubility of Resin-Based Restorative Materials

Influence of Specimen Dimension, Water Immersion Protocol, and Surface Roughness on Water Sorption and Solubility of Resin-Based Restorative Materials

Restorative Dental Resin Functionalized with Calcium Methacrylate with a Hydroxyapatite Remineralization Capacity

Engineered Biomaterials Trigger Remineralization and Antimicrobial Effects for Dental Caries Restoration

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