Fabrication and characterization of novel macroporous hydrogels based on the polymerizable surfactant AAc-Span80 and their enhanced drug-delivery capacity

Abstract

PNIPAM-co-AAc-Span80 shows an enhanced hydrophobic property, rich pore structure, and good adsorption performance for DOX. The desorption results demonstrate that 98.7% of DOX can be released efficiently in an acidic environment.

An oxygen-generating metal organic framework nanoplatform as a “synergy motor” for extricating dilemma over photodynamic therapy

“…Zhang et al 72,73 utilized mesoporous silica Santa Barbara Amorphous-15 (SBA-15) as a delivery carrier, significantly suppressing the aggregation of asarone, and improving the DNA loading capacity in vivo. 74 Tu et al 75 designed macroporous pH-sensitive hydrogels, with a rich pore structure, and the payload stability was enhanced.…”