Fabrication and biological assessment of halloysite-doped micro/nano structures on titanium surface

Zhou, Zixin; Cai, Kexin; Shen, Jiating; Cai, Lei; Dai, Binwei; Wang, Zhen; Ma, Pingping; Liu, Jinsong; Shen, Xinkun

doi:10.1016/j.ceramint.2022.11.044

Cited by 6 publications

(3 citation statements)

References 52 publications

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“…Park et al [99] utilized Ti-6Al-4V ELI discs and subjected them to treatment with pulsed DC power for 3 min at 280 V in electrolytes containing bioactive ions such as Si, Zn, Mg, Mn, Sr, Ca, and P. The energy-dispersive X-ray spectroscopy (EDS) results revealed that the (Ca + Mg + Si + Mn + Zn + Sr)/P ratio was approximately 1.67. Some researchers have directly added HA to the electrolyte [100,101]. Zhou et al [101] dispersed hydroxyapatite nanotubes (HNTs) in the MAO electrolyte and embedded HNTs into the Ti surface.…”

Section: Osteointegrationmentioning

confidence: 99%

“…Some researchers have directly added HA to the electrolyte [100,101]. Zhou et al [101] dispersed hydroxyapatite nanotubes (HNTs) in the MAO electrolyte and embedded HNTs into the Ti surface. When comparing three types of surfaces, Ti, MAO, and MAO-HNT, the HNT group outperformed the Ti and MAO groups in terms of angiogenesis, as evidenced by enhanced cell migration, tube formation, and vascular gene expression in HUVECs.…”

Section: Osteointegrationmentioning

confidence: 99%

“…A good blood supply is essential for successful osseointegration. Studies have found that adulteration of appropriate amounts of Ca [101], Li [102], Se [103], Sr [104], Si [105], and Zn [106] elements can contribute to angiogenesis. Yu et al [106] introduced zinc acetate into the electrolyte to produce coatings enriched with zinc.…”

Section: Osteointegrationmentioning

confidence: 99%

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Micro-Arc Oxidation in Titanium and Its Alloys: Development and Potential of Implants

Ming,

Wu,

Zhang

et al. 2023

Coatings

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Titanium (Ti) and its alloys are widely recognized as preferred materials for bone implants due to their superior mechanical properties. However, their natural surface bio-inertness can hinder effective tissue integration. To address this challenge, micro-arc oxidation (MAO) has emerged as an innovative electrochemical surface modification technique. Its benefits range from operational simplicity and cost-effectiveness to environmental compatibility and scalability. Furthermore, the distinctive MAO process yields a porous topography that bestows versatile functionalities for biological applications, encompassing osteogenesis, antibacterial, and anti-inflammatory properties. In this review, we undertake an examination of the underlying mechanism governing the MAO process, scrutinize the multifaceted influence of various factors on coating performance, conduct an extensive analysis of the development of diverse biological functionalities conferred by MAO coatings, and discuss the practical application of MAO in implants. Finally, we provide insights into the limitations and potential pathways for further development of this technology in the field of bone implantation.

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