F-substituted hydroxyapatite nanopowders: Thermal stability, sintering behaviour and mechanical properties

Bianco, Alessandra; Cacciotti, Ilaria; Lombardi, Mariangela; Montanaro, Laura; Bemporad, Edoardo; Sebastiani, Marco

doi:10.1016/j.ceramint.2009.09.007

Cited by 120 publications

(58 citation statements)

References 33 publications

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“…FHA is beneficial to improve some key properties of HA; it has lower absorbable rate and better bioactivity compared to HA, and hence FHA has the potential to be used as a decent coating material for bioabsorbable magnesium alloys. 25,26 In addition, the biological properties of a coating may be improved if it is made in nanostructural configuration similar to the structure of natural bone. 27 Thus, in this paper, we planned to prepare a nanostructured FHA coating on Mg alloy implants.…”

Section: Materials Science and Engineering: C Vol 48 (March 2015)mentioning

confidence: 99%

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Razavi

Fathi

Savabi

et al. 2015

Materials Science and Engineering: C

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Although magnesium (Mg) is a unique biodegradable metal which possesses mechanical property similar to that of the natural bone and can be an attractive material to be used as orthopedic implants, its quick corrosion rate restricts its actual clinical applications. To control its rapid degradation, we have modified the surface of magnesium implant using fluoridated hydroxyapatite (FHA: Ca10(PO4)6OH2 − xFx) through the combined micro-arc oxidation (MAO) and electrophoretic deposition (EPD) techniques, which was NOT THE PUBLISHED VERSION; this is the author's final, peer-reviewed manuscript. The published version may be accessed by following the link in the citation at the bottom of the page. 2015): pg. 21-27. DOI. This article is © Elsevier and permission has been granted for this version to appear in e-Publications@Marquette. Elsevier does not grant permission for this article to be further copied/distributed or hosted elsewhere without the express permission from Elsevier. Materials Science and Engineering: C, Vol 48 (March3 presented in our previous paper. In this article, the biocompatibility examinations were conducted on the coated AZ91 magnesium alloy by implanting it into the greater trochanter area of rabbits. The results of the in vivo animal test revealed a significant enhancement in the biocompatibility of FHA/MAO coated implant compared to the uncoated one. By applying the FHA/MAO coating on the AZ91 implant, the amount of weight loss and magnesium ion release in blood plasma decreased. According to the histological results, the formation of the new bone increased and the inflammation decreased around the implant. In addition, the implantation of the uncoated AZ91 alloy accompanied by the release of hydrogen gas around the implant; this release was suppressed by applying the coated implant. Our study exemplifies that the surface coating of magnesium implant using a bioactive ceramic such as fluoridated hydroxyapatite may improve the biocompatibility of the implant to make it suitable as a commercialized biomedical product.

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Section: Materials Science and Engineering: C Vol 48 (March 2015)mentioning

confidence: 99%

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Razavi

Fathi

Savabi

et al. 2015

Materials Science and Engineering: C

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“…Many researchers have addressed the influence of fluorine (F) incorporation within apatite lattice on the biological, mechanical and physicochemical properties of HA such as, thermal stability [2], solubility [3], stem cell growth-colonisation [4], hardness, crystallinity and corrosion resistance [5]- [7]. Thus most of the existed studies focussed on qualitative description of the variations in the properties shown by HA and F-HA.…”

Section: Introductionmentioning

confidence: 99%

“…Synthetic hydroxyapatite [HA; Ca 10 (PO 4 ) 6 (OH) 2 ] has been extensively used as an implant material, because of its similarity with human bone composition and thereby its ability to form a strong bond to the human hard tissue. However, synthetic HA presents poor thermal stability.…”

Section: Introductionmentioning

confidence: 99%

X-Ray Peak Profile Analysis of Nanostructured Hydroxyapatite and Fluorapatite

Venkateswarlu¹,

Sreekanth²,

Sandhyarani³

et al. 2012

IJBBB

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“…In vitro studies have confirmed biocompatibility of calcium fluorapatite and have shown release of F -ions in a controlled rate. Moreover, it has been demonstrated that it exhibits integration with hard tissue and longer resorption time that ordinary CaHAp 12,13,15 . Due to these advantages fluorapatite is considered as a biological material and as a fluorescence bioprobe for bio-imaging and biosensing.…”

Section: Introductionmentioning

confidence: 99%

“…It is known that fluorine ions release from CaFAp could lead to inhibition of bacteria metabolism 11 . According to this, F -ions prevent and control dental caries, stimulate bone cells proliferation and differentiation 12 . Furthermore, this essential microelement is necessary for the normal dental and bone formation in living systems 13,14 .…”

Section: Introductionmentioning

confidence: 99%

Effects of crystalline growth on structural and luminescence properties of Ca_(10−3x)Eu_2x(PO₄)₆F₂ nanoparticles fabricated by using a microwave driven hydrothermal process

et al. 2017

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F-substituted hydroxyapatite nanopowders: Thermal stability, sintering behaviour and mechanical properties

Cited by 120 publications

References 33 publications

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

X-Ray Peak Profile Analysis of Nanostructured Hydroxyapatite and Fluorapatite

Effects of crystalline growth on structural and luminescence properties of Ca_(10−3x)Eu_2x(PO₄)₆F₂ nanoparticles fabricated by using a microwave driven hydrothermal process

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F-substituted hydroxyapatite nanopowders: Thermal stability, sintering behaviour and mechanical properties

Cited by 120 publications

References 33 publications

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

X-Ray Peak Profile Analysis of Nanostructured Hydroxyapatite and Fluorapatite

Effects of crystalline growth on structural and luminescence properties of Ca(10−3x)Eu2x(PO4)6F2 nanoparticles fabricated by using a microwave driven hydrothermal process

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Effects of crystalline growth on structural and luminescence properties of Ca_(10−3x)Eu_2x(PO₄)₆F₂ nanoparticles fabricated by using a microwave driven hydrothermal process