F-18 FDG PET/CT Practice Guideline in Oncology

Soydal, Çiğdem; Burak, Zeynep; Uçmak, Gülin; Bozkurt, Murat Fani; Atasever, Tamer; Demirci, Emre; Sivrikoz, İlknur Ak

doi:10.4274/nts.galenos.2020.0028

Cited by 5 publications

(3 citation statements)

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“…Since 2014, the response given to treatment is evaluated according to CT and PET-CT [2]. Today, the most widely used PET radiopharmaceutical is fluorodeoxyglucose (FDG), a glucose analog labeled with Fluor-18 (F-18) [5]. After it is given to the body, it accumulates in the bladder.…”

Section: Introductionmentioning

confidence: 99%

“…However, it is stated that the rate of PET-CT facilities, where patient weight is taken into account, is 44% [3]. In addition, if there is a suspicion of pregnancy or if the breastfeeding process continues, it should be done under the control of a doctor within the scope of certain instructions [5]. Also, positron emission tomography is a medical method with high economic costs [4].…”

Section: Introductionmentioning

confidence: 99%

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A Decision Support System For Detecting Stage In Hodgkin Lymphoma Patients Using Artificial Neural Network and Optimization Algorithms

AKALIN

Orhan

Büyükavcı

2022

Sakarya University Journal of Computer and Information Sciences

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Hodgkin-type lymphoma is a disease with unique histological, immunophenotypic, and clinical features. This disease occurs in nearly 30% of all lymphomas. Its treatable is high. However, the treatment plan is specified after the stage and risk status are determined. For this reason, it is an important process for doctors to decide on the stage of the disease correctly. Some of the data used for this decision are the patient's history, detailed physical examination, laboratory findings, imaging methods and bone marrow biopsy results. Hybrid FDG-PET is the other method used in the medical world. This method is used in diagnosis, evaluation of response given to treatment, staging and restaging process. However, it is radiation-based. Therefore it has the possibility of producing undesirable results in the future. In this study, an artificial intelligence-based computer-assisted decision support system is done to reduce the number of used medical methods and radiation exposure. Data were obtained from the NCBI-GEO dataset. The evaluation of these data, which contains missing values, is handled in two ways. Firstly, samples with missing values in the initial evaluation are deleted from the dataset. Then, these data are trained with “trainlm” function in artificial neural network architecture. However, reducing the error value of the estimates is important. For this, the artificial neural network architecture is retrained with the artificial bee colony algorithm, particle swarm optimization algorithm and invasive weed algorithm, respectively. Secondly, the same operations are performed again on the dataset containing missing values. As a result of the training, the maximum performance was obtained for invasive weed and particle swarm optimization algorithms with 1,45547E+14 and 1,23103E+14 average error rates, respectively.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Decision Support System For Detecting Stage In Hodgkin Lymphoma Patients Using Artificial Neural Network and Optimization Algorithms

AKALIN

Orhan

Büyükavcı

2022

Sakarya University Journal of Computer and Information Sciences

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“…Ancak göreceli tanı için kullanılsa bile pek çok iyi huylu enfeksiyöz/inflamatuar süreç, yüksek bir SUV değeri yani önemli miktarda FDG tutulumu gösterebilir ve bunun tersine, sessiz veya yavaş büyüyen malign süreç, minimum düzeyde alım ve düşük SUV değerlerine sahip olabilir. Tarama ve enjeksiyon arasındaki süre, hasta ağırlığının ölçümü, şırınga artık doz aktivite ölçümü, görüntü kalitesi optimizasyonu, kalibrasyon ve görüntü analizi tam olarak yapılmadığı takdirde SUV>2,5 değerinin kanser tanısında kullanımı geçersiz olabilmektedir(33)(34)(35).Tedavi yanıtının değerlendirilmesi amacıyla18 F-FDG-PET-BT görüntüleme tekrarı için kanserli hastalarda, kemoterapi sonrası 2 veya 3 hafta, radyoterapi sonrası en az 2 ay, tedavi süreç etkisinin azalması için bekleme süresi öngörülmektedir. Non-Hodgkin Lenfoma (NHL) teşhisi konulan hastanın 21 günlük periyotlarla planlanan R-CHOP protokollü kemoterapi tedavisi uygulama öncesi kanserin yaygınlığının belirlenmesi ve 3. kemoterapi sonrası (izlem süreci)18 F-FDG-PET-BT görüntüleri, sırasıyla, Şekil 4 (A ve B) ve Şekil 4 (C ve D)'de verilmiştir.Kemoterapi öncesi alınan görüntülerde (Şekil 4A, B) T4 vertebra hizasında sol parevertabral alan yerleşimli yumuşak doku lezyonu boyutu 39x15mm ve SUV maks :13,8 olarak belirlenmiştir.…”

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Bilgisayarlı Tomografi, Pozitron Emisyon Tomografisi ve Nükleer Manyetik Rezonans Görüntülemede Temel Kavram ve İlkeler

HAMAN BAYARI,

AKIN,

TUNCEL

2023

Batı Karadeniz Tıp Dergisi

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Vücudun normal ve normal olmayan anatomi ve fizyolojisini izlemek için farklı doku ve organlarının invaziv olmayan yöntemlerle görsel temsil işlemi olan medikal görüntüleme, sağlık sektöründe ilgi çekici, vizyoner ve gelişmeye hızla devam eden alanlardan biridir. Röntgen (X-ışın), bilgisayarlı tomografi (BT), pozitron emisyon tomografisi (PET) gibi iyonize radyasyon kullanan, manyetik rezonans görüntüleme (MRG), Ultrason (US) gibi iyonize radyasyon kullanmayan ve bunlardan bazılarının bir arada olduğu hibrid PET-BT gibi birçok medikal görüntüleme tekniği bulunmaktadır. Hassas teşhis, izlem ve kişileştirilmiş tedavi planlamada görüntüleme tekniklerinin etkin bir şekilde kullanılmasını sağlamak için uygulama ve yöntemlerin iyi bilinmesinin yanı sıra riskler hakkında da bilgiye ihtiyaç vardır. Bu derlemede özellikle onkolojide sıklıkla kullanılan BT, PET-BT ve MR görüntüleme tekniklerinin temelleri üzerinde radyofarmasötikler ve ajanlar ile birlikte odaklanılmıştır

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Evaluation of brain metabolism using F18-FDG PET/CT imaging in patients diagnosed with lung cancer

Şen,

Kaya,

Bozcuk

et al. 2024

Nuclear Medicine Communications

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Objectives Brain imaging of regional metabolic changes in cancer patients can provide insights into cancer biology. We aimed to detect regional metabolic changes in the brains of untreated lung cancer patients without brain metastases using 2-deoxy-2-[18F]fluoroglucose PET/computed tomography. Methods The study included 44 lung cancer patients and 17 non-cancer patients as controls. Standardized uptake value (SUV) mean values of 68 different brain regions were recorded, and their ratios to whole brain and brainstem SUVmean were calculated. Results Comparisons between the groups showed significant reductions in the frontal lobe, inferior temporal gyrus, and right cingulate and paracingulate gyrus ratios in the patient group. Conversely, the right nucleus caudatus and right pallidum ratios were elevated. Correlation analysis with total lesion glycolysis (TLG) revealed positive correlations in the basal ganglia, right insula, amygdala, and right hippocampus ratios. Negative correlations were observed in the left frontal lobe and some temporal and parietal regions. Conclusions While most brain regions showed reduced metabolism, potentially due to tumor-brain glucose competition, others were preserved or positively correlated with TLG, suggesting a link to poor prognosis. The reduced metabolism in the frontal lobe might be associated with depression and cognitive decline in cancer patients.

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F-18 FDG PET/CT Practice Guideline in Oncology

Cited by 5 publications

References 0 publications

A Decision Support System For Detecting Stage In Hodgkin Lymphoma Patients Using Artificial Neural Network and Optimization Algorithms

A Decision Support System For Detecting Stage In Hodgkin Lymphoma Patients Using Artificial Neural Network and Optimization Algorithms

Bilgisayarlı Tomografi, Pozitron Emisyon Tomografisi ve Nükleer Manyetik Rezonans Görüntülemede Temel Kavram ve İlkeler

Evaluation of brain metabolism using F18-FDG PET/CT imaging in patients diagnosed with lung cancer

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