Eyespray Vaccination: Infectivity and Development of Immunity to Eimeria acervulina and Eimeria tenella

Chapman, Harold D.; Cherry, Tim E.

doi:10.1093/japr/6.3.274

Cited by 16 publications

(10 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If operated correctly, eye spray equipment can provide a consistent, uniform dose of oocysts to individual birds. Experiments have shown that vaccinated chicks are capable of resisting challenge by 4 weeks of age (Chapman and Cherry, 1997).…”

Section: Methods Of Vaccinationmentioning

confidence: 99%

“…56, March 2000 tion is also important for attenuated vaccines because, if birds are not vaccinated or receive an inadequate dose, they may be susceptible to pathogenic field strains. The proportion of birds truly infected following administration of Coccivac B@ by eye spray was investigated by Chapman and Cherry (1997). Small and medium sized oocysts (probably E .…”

Section: Uniformity Of Vaccine Administrationmentioning

confidence: 99%

See 1 more Smart Citation

Practical use of vaccines for the control of coccidiosis in the chicken

Chapman

2000

World's Poultry Science Journal

View full text Add to dashboard Cite

Section: Methods Of Vaccinationmentioning

confidence: 99%

Section: Uniformity Of Vaccine Administrationmentioning

confidence: 99%

Practical use of vaccines for the control of coccidiosis in the chicken

Chapman

2000

World's Poultry Science Journal

View full text Add to dashboard Cite

“…Live vaccines (Immucox Ò , Coccivac Ò ) based on virulent oocysts or attenuated strains (Paracox Ò , Livacox Ò ) are so far the only products on the market which show signi®cant protective immune responses in the ®eld (Chapman and Cherry 1997;Danforth 1998;Shirley and BedrnõÂ k 1997). With virulent vaccines, adequate management is important because high doses depress weight gains of birds and low doses do not always reduce the severity of lesions.…”

Section: Introductionmentioning

confidence: 99%

Immunity to coccidiosis after treatment with toltrazuril

Greif

2000

Parasitology Research

View full text Add to dashboard Cite

Some characteristics of immune sera after toltrazuril treatment which may be involved in the enhancement of immunity are as follows. Firstly, toltrazuril acts against all intracellular parasite stages from 1 to 168 h post-infection: intracellular schizonts of generations I, II and III and also intracellular gamonts. These damaged stages remain in the host cell for a prolonged time, during which they act as antigens which can be recognised by the immune system. Secondly, immune sera during therapeutic treatment with toltrazuril show a high antibody titre of 1:100 and 1:250 in IFAT after challenge. In the immunoblot, these sera show a strong reaction with low molecular protein fragments between 14 and 20 kDa. Toltrazuril does not interfere with the process of parasite protein recognition by the immune system during infection. Thirdly, there is a tendency for a higher IgG response after treatment with toltrazuril. Fourthly, a higher antibody titre in IFAT, immunoblot and ELISA correlates with a higher reduction in oocyst excretion, lesion scoring and increased weight gains in toltrazuril-treated animals.

show abstract

“…Studies using oocysts irradiated to prevent intracellular development, but not invasion, demonstrated partial protection against challenge infection, thereby suggesting that sporozoites may also be immunogenic [4] Immunity to Eimeria is stimulated by the initial developing parasite stages, particularly the schizonts, and subsequently boosted and maintained by multiple reexposure to oocysts in the litter. Thus, the recycling of infection following administration of live oocysts is critical for the development of protective immunity [5].…”

Section: G1amentioning

confidence: 99%

Assessment of Profile of Antigenicity and Immunogenicity of Eimeria maxima and Eimeria tenella Through Propagative Level and Histopathological Changes in Site Infection for Exploration of Optimal Low Doses of Bivalent Chicken Coccidiosis Live Vaccine

Yunus¹

2018

Proceedings of the 1st International Conference in One Health (ICOH 2017)

View full text Add to dashboard Cite

AbstrakLive vaccines group was the first to be studied, due to the fact that live parasites reduce further reinfection. The development of vaccine to control coccidiosis caused by E. maxima and E. tenella in chickens is intensifying because of the increasing threat of drug resistance to anticoccidial agents. It is important, therefore, to develop a reliable standard method for the assessment of vaccine afficacy particularly antigenicity and immunogenicity become crucial. Evaluation of profile of antigenicity and immunogenicity of E. maxima and E. tenella to some low doses can be reflected through propagative level and histopathological changes. The complete random design of research was used in this study. Sixty of two weeks old broilers were divided into four groups and each group composed 15 replications. The group 1 and group 2 were chicken group inoculated orally 5 x 102 and 1 x 103 virulent E. maxima oocysts, respectively. The group 3 and group 4 were chicken group inoculated with 2.5 x 102 and 5 x 102 virulent E. tenella oocysts, respectively. Then all chickens of group 1 and group 2 were challenged with E. maxima oocyst at doses of 5 x 103, while chicken group 3 and group 4 were challenged with E. tenella oocyst at doses of 2.5 x 103. Observation of research that represented antigenicity and immunogenicity was clinical sign, propagative level, histopathological changes. On primary inoculation, chicken group 1 and 3 which low doses of E. maxima and E. tenella respectively inoculated was some clinical signs such as appetite, weakness, and diarrhea were not seen on all chicken, low parasite propagative level and few histopathological changes on development site, whereas on group 2 and 4 which higher doses of E. maxima and E. tenella respectively inoculated was appeared clinical signs such as appetite, weakness, and diarrhea, moderate parasite propagative level and histopathological changes on development site. Then on challenge test, group 1 and 2 which challenged E. maxima and group 3 and 4 which challenged E. tenella showed there were no clinical signs such as appetite, weakness, and diarrhea on all chicken groups. For the propagative level and histopathological changes, there were no significantly differences in all chicken groups. We concluded that the low doses of virulent E. maxima and E. tenella had low propagative level and few histopathological changes effect that represents a promising strategy to prevent chickens coccidiosis particularly both species.

show abstract

Eyespray Vaccination: Infectivity and Development of Immunity to Eimeria acervulina and Eimeria tenella

Cited by 16 publications

References 3 publications

Practical use of vaccines for the control of coccidiosis in the chicken

Practical use of vaccines for the control of coccidiosis in the chicken

Immunity to coccidiosis after treatment with toltrazuril

Assessment of Profile of Antigenicity and Immunogenicity of Eimeria maxima and Eimeria tenella Through Propagative Level and Histopathological Changes in Site Infection for Exploration of Optimal Low Doses of Bivalent Chicken Coccidiosis Live Vaccine

Contact Info

Product

Resources

About