Eyelid Molluscum Contagiosum Lesions in Two Patients with Unilateral Chronic Conjunctivitis

Serin, Şule; Oflaz, Ayşe Bozkurt; Karabağlı, Pınar; Gedik, Şansal; Bozkurt, Banu

doi:10.4274/tjo.52138

Cited by 16 publications

(20 citation statements)

References 11 publications

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“…In this case, lesions are typically located on the scalp and have a circular arrangement 38. Other sites of atypical location,1 in addition to the oral mucosa, include the palms and soles, the areola/nipple,39,40 the conjunctiva,41 lips,42 eyelids,43 among others 44. Clinical presentation of periocular lesions has been described as erythematous, nodular umbilicated, big/giant, conglomerated, inflamed, or pedunculated 45.…”

Section: Clinical Manifestationsmentioning

confidence: 96%

<p>Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment</p>

Meza‐Romero¹,

Navarrete‐Dechent²,

Downey³

2019

CCID

119

115

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Molluscum contagiosum (MC) is a self-limited infectious dermatosis, frequent in pediatric population, sexually active adults, and immunocompromised individuals. It is caused by molluscum contagiosum virus (MCV) which is a virus of the Poxviridae family. MCV is transmitted mainly by direct contact with infected skin, which can be sexual, non-sexual, or autoinoculation. Clinically, MC presents as firm rounded papules, pink or skin-colored, with a shiny and umbilicated surface. The duration of the lesions is variable, but in most cases, they are self-limited in a period of 6-9 months. The skin lesions may vary in size, shape, and location, which is more frequent in immunosuppressed patients, and could present complications such as eczema and bacterial superinfection. The diagnosis is based on clinical findings. A useful clinical tool is dermoscopy. If the diagnostic doubt persists, confocal microscopy or skin biopsy could be performed. The need for active treatment for MC is controversial; however, there is a consensus that it should be indicated in cases of extensive disease, associated with complications or aesthetic complaints. There are several treatment modalities which include mechanical, chemical, immunomodulatory, and antivirals. The objective of this article is to review the current evidence in etiology, clinical manifestations, diagnosis, and management alternatives of MC.

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Section: Clinical Manifestationsmentioning

confidence: 96%

<p>Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment</p>

Meza‐Romero¹,

Navarrete‐Dechent²,

Downey³

2019

CCID

119

115

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“…It is likely for the primary eye care providers to miss the cutaneous lesions and continue to treat the associated congestion of the conjunctiva as allergic conjunctivitis as demonstrated in our case report. [26] Schornack et al observed that in almost 40% of cases, OMC were not diagnosed in the first visit. [4] Primary skin care providers in their turn need to be aware that MC lesions near the eye may trigger anterior segment inflammation presenting most commonly as unilateral chronic conjunctivitis.…”

Section: Discussionmentioning

confidence: 99%

“…Serin et al and Balakrishnan et al have reported immediate resolution of conjunctivitis as well as keratitis with excision of primary MC lesions around the eyelid. [26] However, surgical or chemical ablative therapies in a periorbital location risks infection and scarring especially in pediatric or immune compromised patients. [2] Cidofovir and Brincidofovir, a broad spectrum lipid conjugate of cidofovir, have been shown to be efficacious in MC lesions.…”

Section: Discussionmentioning

confidence: 99%

“…Ophthalmic MC (OMC) lesions are often located on the eyelid margins or on the lid near the palpebral aperture and may lead to secondary unilateral follicular conjunctivitis and at times superficial punctate keratitis. Uncommonly, subepithelial opacity and pannus and intraocular MC following corneo-scleral laceration is seen,[2345] whereas a primary conjunctival or corneal molluscum lesion is a very rare occurrence. Although simple excision of primary lesion leads to resolution of OMC, till date there has been no approved oral antiviral drug efficacious against MCV.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Successful use of oral acyclovir in ophthalmic molluscum contagiosum

Mutalik

Rasal

2019

Indian Dermatol Online J

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Molluscum contagiosum is a common tropical contagious viral infection, involving the skin and the mucous membranes. Ophthalmic molluscum contagiosum is a relatively uncommon condition presenting as secondary follicular conjunctivitis or kerato-conjunctivitis and may present with or without obvious dermal skin lesions. Often, unsuspected and misdiagnosed by eye care providers or observed as a concomitant feature by a skin care provider, unilateral conjunctivitis due to molluscum contagiosum remains easily treatable. Clearance of the primary skin lesion leads to rapid and complete resolution of ophthalmic signs. Two cases of ophthalmic molluscum contagiosum treated successfully with oral antiviral drug acyclovir are presented herewith as anecdotal therapeutic evidence.

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“…They may occur less commonly in other sites of skin and mucosa including oral cavity and eyelids. [ 1 2 3 ] They can occur on the scalp along with lesions on other sites but lesions localized only to the scalp is quite infrequent. [ 4 5 ] However, lesions over scalp have been described in the past in a newborn[ 6 ] and in children[ 7 8 ] Cases of isolated lesions on the scalp of an adult by Hill and Messina[ 9 ] have been reported in the past in the western literature.…”

mentioning

confidence: 99%