“…(4) The integral evaluation of this case includes complete and detailed anamnesis, physical examination, full blood count, metabolic panel, total body computed tomography and bone marrow biopsy. (5) As a neoplastic tumor, different treatment options need to be considered, included but not limited to radiotherapy, cryotherapy, chemotherapy, and surgical excision, The most common treatment for low grade lesions are removal by radiotherapy, but it depends also on the ophthalmological center experience, the access to the technology, and the ability of the surgical team. On the other hand, it depends on the extension, localization, and dissemination of the lesion.…”