Eye-motion-corrected optical coherence tomography angiography using Lissajous scanning

Abstract

Abstract:To correct eye motion artifacts in en face optical coherence tomography angiography (OCT-A) images, a Lissajous scanning method with subsequent software-based motion correction is proposed. The standard Lissajous scanning pattern is modified to be compatible with OCT-A and a corresponding motion correction algorithm is designed. The effectiveness of our method was demonstrated by comparing en face OCT-A images with and without motion correction. The method was further validated by comparing motion-corrected images with scanning laser ophthalmoscopy images, and the repeatability of the method was evaluated using a checkerboard image. A motion-corrected en face OCT-A image from a blinking case is presented to demonstrate the ability of the method to deal with eye blinking. Results show that the method can produce accurate motion-free en face OCT-A images of the posterior segment of the eye in vivo. Y. Jia, "Automated motion correction using parallel-strip registration for wide-field en face OCT angiogram," Biomed.

Ultrahigh-resolution optical coherence tomography/angiography with an economic and compact supercontinuum laser

“…Although the number of motion artifacts can be decreased by reducing the A-scan number for each B-scan, the imaging quality is accordingly degraded. To effectively eliminate motion artifacts, different methods were used in previous studies, which could be also applicable to the developed UHR-OCT system [42,43].…”

Clinical prototype of pigment and flow imaging optical coherence tomography for posterior eye investigation

“…The DOPU weighted retinal en face OCT-A allowed the clear visualization of retinal microvasculature without retinal layer segmentation. The eye motion was corrected using previous method [ 45 ]. A modified Lissajous scanning pattern with two repeated cycles with 724 A-lines and 724 cycles (two periods of Lissajous pattern) was used.…”

“…The kernel size for OCT-A processing was 5 pixels (21.6 μ m) along the axial direction for complex averaging. Because the acquisition time was long, the subject blinked once during the scan; however, the Lissajous motion correction algorithm tolerated the blink and removed and filled blank scanning cycles [ 45 ]. Motion-free en face views of the posterior part of the eye and retinal vasculature were obtained.…”

Handheld spectrally encoded coherence tomography and reflectometry for motion-corrected ophthalmic optical coherence tomography and optical coherence tomography angiography

“…Motion also significantly affects OCTA postprocessing, resulting in regions of high decorrelation contrast and vascular discontinuities. 12 Previously described methods for reducing OCT motion artifacts include higher speed image acquisition, [13][14][15] combinations of scan patterns with computational postprocessing, 5,[16][17][18][19] and optical tracking. [20][21][22] However, the added system and/or computational complexity often limit their application to benchtop systems.…”