Extremely Late In-Stent Thrombosis 12 Years After Implantation of a Drug-Eluting Stent

Abstract

Stent thrombosis is one of the most feared complications of percutaneous coronary intervention. Most commonly it occurs within the first few days after the deployment of the stent. Once the stent is completely endothelialized, this complication becomes extremely rare. Few cases of very late stent thrombosis were reported in the literature with the longest interval being around 11 years after the initial intervention. We report here the case of a 78-year-old male patient who presented with acute onset chest pain found to have acute inferior ST-segment elevation myocardial infarction due to thrombotic occlusion of a prior paclitaxel drug-eluting stent placed 12 years prior. This is, to our knowledge, the first case of stent thrombosis occurring after this long duration since stent implantation.

Extremely Late Stent Thrombosis in a First Generation Drug- Eluting Stent 10 Years After Stent Deployment: A Case Report

“…VLST is extremely rare after 5 years of stent implantation, and the first case was reported in 2009 5 . In the literature, there are a very few case reports regarding extremely LST due to first-generation DES with the longest reported period being 12 years [6][7][8] . To the best of our knowledge, this is the first case report with the longest duration (10 years) after sirolimus eluting first-generation DES in Bangladesh and 3 rd case report with the longest duration in the literature (first longest duration 12 years and second longest duration 11 years) 7,8 .…”

“…In the literature, there are a very few case reports regarding extremely LST due to first-generation DES with the longest reported period being 12 years [6][7][8] . To the best of our knowledge, this is the first case report with the longest duration (10 years) after sirolimus eluting first-generation DES in Bangladesh and 3 rd case report with the longest duration in the literature (first longest duration 12 years and second longest duration 11 years) 7,8 . We report a case of extremely LST occurring 10 years after first generation DES implantation in a patient presented with acute inferior ST-segment elevation myocardial infarction (STEMI).…”