Extremely high-dose insulin requirement in a diabetic patient with psychiatric illness: A case report
Kibret Enyew Belay,
Beza Leulseged Ayalew,
Abdissa Meherete Etana
et al.
Abstract:Severe insulin resistance is defined as the need of insulin requirement of more than two units per kilogram of body weight. It is rarely seen in diabetic patients. Common causes of severe insulin resistance include severe insulin resistance syndromes, drugs, endocrine disorders, factitious causes, lipodystrophy, increased insulin clearance, and impaired insulin absorption. Here, we describe a diabetic patient with major depressive disorder who was prescribed a maximum of 282 units (4.9 units/kg) of insulin a d… Show more
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