Extreme Sleep Durations and Increased C-Reactive Protein: Effects of Sex and Ethnoracial Group

Abstract

In a representative sample of American adults, elevated CRP was associated with extreme sleep durations. Sex, race/ethnicity, sleep disorders, and medical comorbidity influenced these associations. Differences in CRP along these dimensions should be considered in future research on sleep related disparities influencing cardiometabolic disease risk.

Psychological Distress Mediates the Association between Food Insecurity and Suboptimal Sleep Quality in Latinos with Type 2 Diabetes Mellitus

“…Sleep is a basic biological need that, when disturbed, is associated with metabolic disease risk (1)(2)(3)(4)(5)(6), including diabetes mellitus (7,8). The present guidelines recommend 7-8 h of sleep within a 24-h period for adults to 2 Author disclosures: A Bermúdez-Millán, R Pérez-Escamilla, S Segura-Pérez, G Damio, J Chhabra, CY Osborn, and J Wagner, no conflicts of interest.…”

302. Sleep Onset Insomnia, Daytime Sleepiness and Sleep Duration in Relationship to Toxoplasma gondii IgG Seropositivity and Serointensity

“…To the best of our knowledge, there are no previous studies examining the possible relationship between markers of T. gondii infection, sleep duration and daytime sleepiness. Specifically, while the low-grade immune activation necessary to hold T. gondii in check [68][69][70][71][72], and the associations of up-regulated inflammation with longer sleep duration [73][74][75], would lead to hypothesizing an increased EDS and increased sleep duration in T. gondii-positive individuals, the DA producing theory would lead to hypothesizing a decreased EDS and decreased sleep duration. Thus, probably because of these potential contrasting effects, we did not find any association between sleepwake disturbance and T. gondii seropositivity or serointensity after adjustment for confounders.…”

Sueño y sistema inmune

“…La privación parcial de sueño repetida por varios días produce incremento en la producción de proteína C reactiva (PCR), 44,45 IL-6, 46,47,48 TNF, 49,50 e IL-1β, 45,51 el cual persiste aún después de una noche completa de recuperación del sueño. Estas moléculas activan a NF-κB, la vía de control de transcripción clave en la cascada de señalización infl amatoria.…”