Extraventricular neurocytoma in the left temporal lobe: A case report and review of the literature

Abstract

Central neurocytoma (CNC) often develops in the ventricular system adjacent to the interventricular foramen and septum pellucidum. According to the World Health Organization, CNCs are classified as grade II tumors, and in recent years it has been reported that CNCs have occasionally occurred in rare areas of the central nervous system. The current study describes a rare case of CNC located in the left temporal lobe of a 49-year-old man, who had been experiencing headaches for 3 weeks. Computed tomography identified a round, well-demarcated, 3.3-cm tumor in the left temporal lobe. The patient underwent surgery and the tumor was totally resected. Histological analysis demonstrated that the resected tumor tissue contained clusters of small cells with regular nuclear morphology, and round nuclei with fine chromatin. Immunohistochemically, neuronal differentiation markers, including synaptophysin and neuronal nuclear antigen, were expressed in the tumor cells. Histopathological examination of the resected tissue confirmed a diagnosis of extraventricular neurocytoma. Magnetic resonance imaging was performed at 3 months post-surgery and demonstrated no evidence of tumor recurrence.

Awake craniotomy in an adolescent patient with an extraventricular neurocytoma

“…Gross total resection (GTR) is considered as the treatment of choice for CNC. Despite little data are available, also for EVN the best management should involve surgical resection4 14 15 even if a more aggressive behaviour of these tumours compared with CNC is reported 11. EVN is more often larger in dimensions and may be in or near eloquent areas, thus reducing the possibility of total resection.…”

Mesial temporal extraventricular neurocytoma (mtEVN): A case report and literature review

“…However, there are notable radiological differences between ntEVNs and mtEVNs. On imaging, ntEVNs tended to be more well-defined, contain both solid and cystic components [2] , [14] , [16] , contain frequent calcifications [2] , [16] , [17] , [18] , [19] , and vary in terms of contrast-enhancement, with the majority enhancing [14] , [16] , [19] , [20] , [21] . In contrast, mtEVNs are less clearly demarcated from the surrounding mesial structures, distinctly lack calcifications, and express no enhancement after contrast administration in any of the 6 cases.…”

“…EVNs encompass a large differential, including glial and glioneuronal neoplasms like oligodendrocytomas, ependyomas, and dysembryoplastic neuroepithelial tumors [22] . The current literature says that helpful diagnostic aids in identifying EVNs include the presence of well-defined margins, focal calcifications, cystic changes, and contrast-enhancement [20] , [21] . These radiologic indicators are conspicuously missing in mtEVNs, illustrating the wide morphological spectrum of EVNs.…”

Orbital Meningoencephalocele Due to Extraventricular Neurocytoma: Case Report

“…Extraventricular Neurocytoma (EVN) is a rare primary tumor of Central Nervous System (CNS) [1], -grade II according to World Health Organization (WHO) classifi cation [2,3], that commonly manifests in young adults with partial seizures, headache or focal neurological defi cits [4][5][6]. Conversely, Central Neurocytoma tipically presents with signs and symptoms of intracranial increased pressure and hydrocephalus [6].…”