Extravascular lung water indexed to predicted body weight is a novel predictor of intensive care unit mortality in patients with acute lung injury*

Abstract

Early measurement of predicted extravascular lung water is a better predictor than actual extravascular lung water to identify patients at risk for death in acute lung injury/acute respiratory distress syndrome.

The precision of PiCCO®measurements in hypothermic post‐cardiac arrest patients

“…This result was greater than the reference value (SD) of 7.4 (3.3) ml.kg )1 [17], which suggests an increased risk for pulmonary oedema [33,34]. Moreover, the pulmonary vascular variability index varied from 0.6 to 10.4.…”

“…The detailed principles and the validation of these single-indicator transpulmonary thermodilution-derived variables have been discussed elsewhere [17,[30][31][32]. The extravascular lung water was indexed using predicted body weight [17,33,34].…”

Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial

“…The damage to the alveolar barrier is central to the development of non-cardiogenic pulmonary oedema resulting in acute respiratory failure with refractory hypoxia and the requirement for mechanical ventilation. We have also demonstrated that increased pulmonary oedema is associated with reduced survival in patients with ALI (Craig, Duffy et al 2009). In ALI patients with a markedly elevated dead space fraction has been identified as an independent predictor of mortality [21].…”

Extravascular Lung Water and Sepsis

“…Bir çok çalışmada gerçek vücut ağırlığı ("ABWI:actual body weight index") kullanılırken son yıllarda yapılan çalışmalarda tahmini vücut ağırlığı ("PBW: predicted body weight") indeksinin kullanımının daha faydalı olduğu belirtilmiştir (20)(21)(22)(23) . Teorik olarak ABW indeksine oranla PBWI kullanımı, daha doğrudur.…”