Extraskeletal osteosarcoma: A very rare case report of primary tumor of the colon–rectum and review of the literature

Osteosarcoma

“…The remaining cases are scattered amongst other bones in the body including the fibula, radius, ulna, ribs, jaw, spine, etc. It should also be noted, that despite being very rare, the possibility of extraosseous osteosarcoma also exists [10]. However, these extraskeletal lesions are somewhat controversial, as some may be misdiagnosed forms of other soft tissue sarcomas.…”

“…Most commonly they present in the extremities, but have been reported in the breast, heart, and colon amongst other visceral organs [10,[34][35][36]. There may be an association with prior radiation.…”

“…They are of mesenchymal origin, high-grade, and produce the characteristic osteoid histologically. Treatment is similar to other soft tissue sarcomas and includes resection and possible radiation, but is beyond the scope of this paper [10].…”

Primary osteosarcoma of the parotid gland: A case report and literature review

“…[1] Extraskeletal osteosarcoma of gall bladder, esophagus, colon-rectum, larynx, pleura, kidney, small intestine, liver, heart, urinary bladder and breast are also have been reported in the literature. [2,[6][7][8][9][10][11] However, primary extraskeletal osteosarcoma in the parotid gland is extremely rare. Only five cases have been reported.…”

“…[1] Visceral involvement also have been reported. [2,[6][7][8][9][10][11] Since 1980s (see Table 1), [12,13] only five cases of primary osteosarcomas in the parotid gland were reported in the literature.…”