Extraskeletal Ewing's sarcoma mimicking traumatic hematoma

Abstract

We describe the clinical course of a 16-year-old baseball player with a history of recurrent hematoma of the thigh. The lesion was aspirated percutaneously several times and curetted under the diagnosis of traumatic hematoma. Microscopical examination revealed massive hemorrhage, necrosis, and a small number of Ewing's sarcoma cells. He died of multiple metastases. With recurrent hematoma in the soft tissue, neoplastic lesions should be ruled out.

Alveolar Rhabdomyosarcoma Causing Acute Compartment Syndrome of the Forearm: A Case Report and Review of the Literature

“…Given the vascularity of this patient's tumor, we initially considered a chronically expanding hematoma within the tumor itself, or an acutely expanding hematoma secondary to some minor trauma as the etiology of the compartment syndrome. Large hematomas have been shown within the lesions of angiogenic tumors such as angiosarcoma [20], synovial sarcoma [21][22][23], epitheloid sarcoma [24,25], extraskeletal Ewing's sarcoma [26], leiomyosarcoma [27], liposarcoma [28], or malignant fibrous histiocytoma [29]. However, the timing of the acute increase in pain and the features of the magnetic resonance imaging did not suggest a hematoma as the etiology.…”

Soft-Tissue Sarcoma Mimicking Large Haematoma: A Report of Two Cases and Review of the Literature

“…Large haematomas can form within the lesions of angiogenic tumours 11 (e.g. haemagioma and angiosarcoma), synovial sarcoma, 9,12,13 epithelioid sarcoma, 14,15 extraskeletal Ewing's sarcoma, 16,17 leiomyosarcoma, 16 liposarcoma, 18 rhabdomyosarcoma, 18 or malignant fibrous histiocytoma. 19 Romero et al 15 reported haemorrhagic characteristics in 17% of patients with epithelioid sarcoma using MRI.…”

Calcifying Haematoma Mimicking a Soft Tissue Sarcoma and Myositis Ossificans

“…Although calcifying haematoma is capable of simulating soft tissue sarcomas, the opposite can also occur as illustrated in a case report of a 16‐year‐old boy who presented with a recurrent haematoma of the thigh and had a microscopic analysis that showed a small number of Ewing’s sarcoma cells. He subsequently died of multiple metastases and the authors’ recommendation was that with ‘recurrent haematoma’ in the soft tissue, neoplastic lesions should always be ruled out 3 …”

“…He subsequently died of multiple metastases and the authors' recommendation was that with 'recurrent haematoma' in the soft tissue, neoplastic lesions should always be ruled out. 3 Myositis ossificans was a consideration here because of the extensive calcification seen in the muscle and soft tissue. However, the characteristic 'zonal distribution' of ossification with peripheral maturation was absent.…”