Extrapulmonary tuberculous infection manifested as peritoneal fluid eosinophilia in a continuous ambulatory peritoneal dialysis patient

Hsu, Shih-Chang; Lan, Rong-Ru; Tseng, Chin Chung; Lai, Ching-Te; Huang, Jeng-Jong

doi:10.1093/ndt/15.2.284

Cited by 7 publications

(7 citation statements)

References 7 publications

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“…The PD fluid usually contains increased numbers of neutrophils early on, followed by a lymphocytosis. A monocytosis may also be obser ved (10). The clinical presentation is indistinguishable from more common causes, but is suggested by a history of TB disease, exposure, or risk factors such as an abnormal chest x ray and ethnic background.…”

Section: Increased Numbers Of Neutrophilsmentioning

confidence: 99%

Sterile Peritonitis in the Peritoneal Dialysis Patient

Freitas

Gokal

2005

Perit Dial Int

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Peritonitis is a serious and common problem in the peritoneal dialysis (PD) population. Abdominal pain, fever, and cloudy PD fluid usually heralds the onset of infective peritonitis. However, in up to 20% of cases, no organism is identified. In these situations, diagnosis can be made only by excluding a microbiological cause and performing a cytological examination of the PD fluid to determine the cellular or noncellular constituents. This review examines the differential diagnosis of sterile peritonitis and uses cytological examination to facilitate the appropriate diagnosis.

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Section: Increased Numbers Of Neutrophilsmentioning

confidence: 99%

Sterile Peritonitis in the Peritoneal Dialysis Patient

Freitas

Gokal

2005

Perit Dial Int

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“…reported that patients undergoing peritoneal dialysis had modest peripheral blood and peritoneal fluid eosinophilia. The eosinophilia persisted despite the cessation of dialysis, but it disappeared following the initiation of antituberculous treatment 14 . Similarly, Haftu et al.…”

Section: Discussionmentioning

confidence: 86%

Tuberculosis manifesting with significant peripheral eosinophilia: A case report and review of literature

Damera,

Gupta,

Farooqi

et al. 2023

Clinical Case Reports

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Key Clinical MessagePeripheral eosinophilia is a rare but potential sign of TB infection. Physicians should assess patients for TB, especially if they display related symptoms or risk factors, and consider TB as a differential diagnosis, especially in idiopathic cases.AbstractMillions of new tuberculosis (TB) cases are reported annually. Peripheral eosinophilia is rare in tuberculosis. We describe a rare case of tuberculosis with a high peripheral eosinophil count. A 9‐year‐old male presented with fever, cough, and respiratory discomfort for a month. The patient's cough did not respond to treatment, along with weight loss and a loss of appetite. A physical examination revealed cervical lymphadenopathy and bilateral lung crepitations. A hematological investigation showed a high eosinophil count of 25,920 cells per cubic millimeter and medical imaging abnormalities consistent with TB. Some malignancies, allergies, and parasitic infections produce peripheral eosinophilia. However, medical literature rarely discusses TB‐induced eosinophilia. Several studies attribute it to mycobacterium antigen hyperreactivity. Eosinophilic release of cytotoxic chemicals may cause tissue damage, and TB patients' eosinophil levels may fluctuate. This case report emphasizes the need to investigate TB in peripheral eosinophilia patients after ruling out other explanations. Our patient benefited from early detection and anti‐TB medication. More studies are required to investigate the causes of TB eosinophilia and its consequences. A detailed medical history and physical examination are essential to diagnose and treat atypical presentations of TB.

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“…While eosinophils in pleural effusions have been described in several clinical settings, they are less commonly found in peritoneal fluids. Eosinophils in peritoneal fluid specimens have been mainly described in patients undergoing peritoneal dialysis with or without concurrent intra‐abdominal infections …”

Section: Discussionmentioning

confidence: 99%