Extrapelvic bowel resection and anastomosis in cytoreductive surgery for ovarian cancer

Son, Joo-Hyuk; Chang, Suk-Joon

doi:10.21037/gs-2019-ursoc-01

Cited by 5 publications

(3 citation statements)

References 15 publications

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“…For skilled gynecologic oncologists, the scores of diffuse small bowel adhesions/thickening and surgical difficulty were not completely consistent. Bowel resection surgery can be performed better by skilled gynecologic oncologists (15). Removing retroperitoneal lymph nodes above the IMA that are not adhered to blood vessels also cannot stuff skilled gynecologic oncologists.…”

Section: Discussionmentioning

confidence: 99%

Validation of models in predicting residual disease in ovarian cancer: comparing CT urography with PET/CT

et al. 2023

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Background Many ovarian cancer (OC) residual-disease prediction models were not externally validated after being constructed, the clinical applicability needs to be evaluated. Purpose To compare computed tomography urography (CTU) with PET/CT in validating models for predicting residual disease in OC. Material and Methods A total of 250 patients were included during 2018–2021. The CTU and PET/CT scans were analyzed, generating CT-Suidan, PET-Suidan, CT-Peking Union Medical College Hospital (PUMC), and PET-PUMC models. All imagings were evaluated by two readers independently, then compared to pathology. According to surgical outcomes, all patients were divided into the R0 group, with no visible residual disease, and the R1 group, with any visible residual disease. Logistic regression was used to assess the discrimination and calibration abilities of each model. Results CTU and PET/CT showed good diagnostic performance in predicting OC peritoneal metastases based on the Suidan and PUMC model (all the accuracies >0.8). As for model evaluation, the value of correct classification of the CT-Suidan, PET-Suidan, CT-PUMC, and PET-PUMC models was 0.89, 0.84, 0.88, and 0.83, respectively, representing stable calibration. The areas under the curve (AUC) of these models were 0.95, 0.90, 0.91, and 0.90, respectively. Furthermore, the accuracy of these models at the optimal threshold value (score 3) was 0.75, 0.78, 0.80, and 0.80, respectively. All two-paired comparisons of the AUCs and accuracies did not show a significant difference (all P > 0.05). Conclusion CT-Suidan, CT-PUMC, PET-Suidan, and PET-PUMC models had equal abilities in predicting the residual disease of OC. The CT-PUMC model was recommended for its economic and user-friendly characteristics.

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Section: Discussionmentioning

confidence: 99%

Validation of models in predicting residual disease in ovarian cancer: comparing CT urography with PET/CT

et al. 2023

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“…Ovarian cancer is prone to involve the small intestine or colon, so resection of intestinal metastases is a key part of cytoreductive, and intestinal surgery includes intestinal resection, intestinal tumor stripping. The decision of whether to perform intestinal resection and the extent of resection often needs to be made in conjunction with the intraoperative situation [39]. Reports of intestinal resection have been published to increase optimal debulking surgery rates and improve patient survival [40] [41], however, extension of the surgical scope is associated with higher rates of intraoperative and early postoperative complications (e.g., bleeding, anastomotic dehiscence, and infection) [42].…”

Section: Intestinal Surgerymentioning

confidence: 99%

Trends in Extra-Ovarian Cancer Tissues and Organs Resection in Patients with Ovarian Cancer

Wang¹,

Linghu²

2023

JBM

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Ovarian cancer mostly presents with extensive peritoneal cavity and extraperitoneal dissemination. Satisfactory and complete resection of the lesions is one of the key factors to improve the prognosis. The trend of surgical resection of extra-ovarian tissues and organs invaded by the tumor has become obvious in order to remove all primary loci and all metastases as much as possible to minimize residual tumor lesions. This article provides a literature review on organ resection in ovarian cancer cytoreduction, summarizing the perioperative complications and survival outcomes at the time of different organ surgery, with the aim of providing guidance for clinical work.

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“…Bowel metastasis frequently occurs with advanced ovarian cancer, and debulking cytoreduction surgery, especially en bloc cytoreduction, is recommended ( 1 – 3 ). Bowel resection is performed when bowel metastasis is observed before or during surgery, and it is followed by primary anastomosis or ostomy ( 4 – 7 ). Primary anastomosis is the first choice after bowel resection, and ostomy is the alternative choice.…”

Section: Introductionmentioning

confidence: 99%

Ostomy Does Not Lead to Worse Outcomes After Bowel Resection With Ovarian Cancer: A Systematic Review

2022

Front. Oncol.

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BackgroundDebulking cytoreduction surgery with bowel resection is a common intervention for ovarian cancer. It is controversial whether ostomy causes worse survival outcomes and how clinical physicians should choose which patients to undergo ostomy. During this study, we performed a systematic review to determine whether ostomy leads to worse outcomes after bowel resection compared to anastomosis. We also summarized the possible indications for ostomy. MethodsWe searched PubMed, Embase, and Cochrane for articles containing the phrase “ovarian cancer with bowel resection” that were published between 2016 and 2021. We included studies that compared primary anastomosis with ostomy. We mainly focused on differences in the anastomotic leakage rate, length of hospital stay, overall survival, and other survival outcomes associated with the two procedures.Results and ConclusionOf the 763 studies, three were ultimately included in the systematic review (N=1411). We found that ostomy did not contribute to worse survival outcomes, and that the stoma-related complications were acceptable. Indications for ostomy require further study. Bowel resection segment margins and the distance from the anastomosis to the anal verge require consideration.

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Extrapelvic bowel resection and anastomosis in cytoreductive surgery for ovarian cancer

Cited by 5 publications

References 15 publications

Validation of models in predicting residual disease in ovarian cancer: comparing CT urography with PET/CT

Validation of models in predicting residual disease in ovarian cancer: comparing CT urography with PET/CT

Trends in Extra-Ovarian Cancer Tissues and Organs Resection in Patients with Ovarian Cancer

Ostomy Does Not Lead to Worse Outcomes After Bowel Resection With Ovarian Cancer: A Systematic Review

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