Extraovarian primary peritoneal carcinoma: staging with 18F-FDG PET/CT

Rakheja, Rajan; Makis, William; Hickeson, Marc

doi:10.1007/s00261-011-9722-0

Cited by 8 publications

(5 citation statements)

References 33 publications

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“…Even without final differentiation between malignancies, the use of PET/CT employing 18 F-FDG has been well established for assessing the biological activity and presence of a suspicious mass [11]. …”

Section: Discussionmentioning

confidence: 99%

Extraovarian Primary Peritoneal Carcinomatosis: A Case Report

Nicolas¹,

Kfoury²,

Fawaz³

et al. 2017

Am J Case Rep

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Patient: Female, 66Final Diagnosis: Extraovarian primary peritoneal carcinomatosisSymptoms: Abdominal distension with constipation of 3 days, while still passing flatus. She further complained of mild postprandial epigastric pain, but denied nausea or vomiting as well as feverMedication: —Clinical Procedure: —Specialty: SurgeryObjective:Rare diseaseBackground:Extraovarian primary peritoneal carcinoma (EOPPC) is a rare malignant epithelial tumor with an age-adjusted incidence rate of 6.78 per million, which arises from the peritoneal lining with minimal or no ovarian involvement. EOPPC is a diagnosis of exclusion with the absence of other identifiable primary sites and after surgical assessment and consideration of the histological report to evaluate the extent of ovarian invasion.Case Report:A 66-year-old woman complained of mild postprandial epigastric pain. Physical exam revealed positive bowel sounds over all 4 quadrants, with a soft, non-tender abdomen. Distension and dullness to percussion were noted. A CT scan revealed peritoneal fluid, and evaluation of the peritoneal fluid showed an elevated white blood cell count, while fulfilling criteria for exudate. There was no bacterial growth from the peritoneal fluid. Serum tumor markers CEA were significantly elevated, suggestive of an underlying malignancy. An exploratory laparoscopy confirmed diffuse carcinomatosis in the omentum, the coloparietal region bilaterally, as well as surrounding small bowel loops, the transverse and sigmoid colon, and the rectum. A bilateral oophorectomy was performed and 2 biopsies from the thickened peritoneum were taken. The histomorphological features from the pathology examination concluded the patient had peritoneal serous carcinoma with uninvolved ovaries.Conclusions:EOPPC may be misdiagnosed as epithelial ovarian cancer, and should be considered in patients with peritoneal carcinomatosis, normal-sized ovaries, and no identifiable primary lesion. Since the common therapeutic strategies achieve comparable survival rates, failed recognition may be without consequences. However, to further improve survival, optimal cytoreductive surgery is essential and should be made a priority in disease management.

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Section: Discussionmentioning

confidence: 99%

Extraovarian Primary Peritoneal Carcinomatosis: A Case Report

Nicolas¹,

Kfoury²,

Fawaz³

et al. 2017

Am J Case Rep

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“…Therefore, symptoms of PPSC are similar to those of peritoneal carcinomatosis. Furthermore, the majority patients described in case reports to date were diagnosed in the advanced stages of the disease (7,8). Traditionally, a diagnosis of PPSC is based on the Gynecology Oncology Group criteria, as follows: i) The ovaries are either absent or normal in size; ii) the involvement of the extraovarian sites is greater than the involvement of the surface of either ovary; iii) the absence of a deep-seated invasive ovarian carcinoma or invasive disease in the ovarian cortical stroma with tumors that measuring <5x5 mm 2 ; and iv) histopathological and cytological characteristics of the tumors similar to those for epithelial ovarian cancer (3).…”

Section: Discussionmentioning

confidence: 99%

Primary peritoneal serous carcinoma, an extremely rare malignancy: A case report and review of the literature

Yun¹,

Bae²

2016

Oncology Letters

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Abstract. Primary peritoneal serous carcinoma (PPSC) is an extremely rare malignancy that was first described in 1959. This type of cancer arises from the peritoneal epithelium and is similar to serous ovarian carcinoma. A diagnosis of PPSC is typically made based on the Gynecology Oncology Group criteria; however, a correct differential diagnosis of PPSC is difficult preoperatively. The current study describes the case of a 66 year-old female patient presenting with abdomen distension. A computed tomography (CT) scan revealed abundant ascites in the abdominal cavity and omental infiltration. The results of positron emission tomography/CT showed hot uptake in the greater omentum. Furthermore, preoperative serum cancer antigen-125 levels were 1,032 U/ml. Upon surgical exploration, a whitish mass and nodule were found in the greater omentum. Therefore, omentectomy was performed. Pathological examination of the resected specimen revealed a diagnosis of PPSC. PPSC is extremely rare with few cases cited in the current literature. The present study describes a rare case of PPSC with a review of the literature.

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“…Gegenüber der MRT bietet die PET/CT den weiteren Vorteil, dass hiermit der gesamte Körper erfasst wird und somit auch eine Aussage über extraabdominale Tumormanifestationen möglich ist [34]. …”

Section: Präoperative Bildgebungunclassified

Peritonealkarzinose: Präoperative Diagnostik und Patientenselektion

Koenigsrainer¹,

Struller²,

Horvath³

et al. 2013

Visc Med

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Hintergrund: Die zytoreduktive Chirurgie und die hypertherme intraperitoneale Chemotherapie spielen inzwischen eine zunehmend wichtige Rolle in der Therapie der Peritonealkarzinose bei zahlreichen Tumorentitäten. Methode: Die wichtigsten Selektionskriterien werden erläutert. Ergebnisse: Neben dem Alter und Allgemeinzustand sowie der Auswahl geeigneter Tumorentitäten spielt die Tumorlast, die möglichst exakt bereits vor der Operation abgeschätzt werden sollte, eine entscheidende Rolle. Schlussfolgerung: Entscheidend ist eine Selektion geeigneter Patienten, um den onkologischen Benefit zu steigern und die Morbidität zu verringern.

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Extraovarian primary peritoneal carcinoma: staging with 18F-FDG PET/CT

Cited by 8 publications

References 33 publications

Extraovarian Primary Peritoneal Carcinomatosis: A Case Report

Extraovarian Primary Peritoneal Carcinomatosis: A Case Report

Primary peritoneal serous carcinoma, an extremely rare malignancy: A case report and review of the literature

Peritonealkarzinose: Präoperative Diagnostik und Patientenselektion

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