Extraosseous uptake of 99mTechnetium phosphate in an extremity

Ozalp, Elcin; Yagcioglu, Hulya; Ibis, Erkan; Araş, Gülseren; Erbay, Güner; Akin, Asim

doi:10.1016/s0001-2998(95)80009-3

Seminars in Nuclear Medicine

1995

DOI: 10.1016/s0001-2998(95)80009-3

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Extraosseous uptake of 99mTechnetium phosphate in an extremity

Elcin Ozalp

Hulya Yagcioglu

Erkan Ibis

et al.

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Cited by 3 publications

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“…Inadvertent intra-arterial injections of various radiopharmaceuticals are well known. A bone imaging agent, such as technetium-99m ( 99 Tc m ) methylene diphosphonate (MDP), when injected into the artery at the antecubital fossa or wrist results in a ''glove phenomenon'' or ''glove-like pattern'' of distribution of radioactivity [1][2][3][4]. Here, the intra-arterial injection of 18Ffluorodeoxyglucose (18F-FDG) and its uptake in the tissues distal to the injection are described.…”

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confidence: 99%

Abnormally increased uptake of 18F-FDG in the forearm and hand following intra-arterial injection — hot forearm and hot hand signs

Kumar

2009

BJR

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The aim of this study is to describe the appearance of intra-arterial administration of 18F-fluorodeoxyglucose (18F-FDG). The effect of this finding on the standard uptake values (SUVs) is also briefly discussed. Three cases of 18F-FDG positron emission tomography (PET) scans, detected over 2 years (2004-2006), with different presentations producing hot forearm and hot hand signs are described. It was shown that intra-arterial injections of 18F-FDG producing "the hot forearm sign" and the hot hand sign" are similar to the glove pattern of uptake noted following intra-arterial administration of technetium-99m methylene diphosphonate. Following intra-arterial injection, uptake of 18F-FDG is accentuated by hypoxia and exercise. A comparison is also made with the pattern of soft-tissue uptake seen following true intravenous injections with similar pre-injection vein enhancement techniques to the intra-arterial injections. Evaluation of the maximum intensity projection (MIP) and transaxial PET/CT fusion images of the arm, forearm and hand helps to confirm the diagnosis. Hands are often not included in PET/CT imaging and therefore cases might be missed. In conclusion, intra-arterial injection of 18F-FDG produces a "hot forearm sign" and "hot hand sign". Hands are often not included in PET/CT imaging, and therefore the presence of hot forearm sign should suggest further investigation. It should be mentioned in the radiology report, as it may alter the sensitivity and specificity of the SUV value.

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confidence: 99%

Abnormally increased uptake of 18F-FDG in the forearm and hand following intra-arterial injection — hot forearm and hot hand signs

Kumar

2009

BJR

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Compartment Syndrome Caused by Computed Tomography Contrast Infiltration Seen on a Tc-99m Methylene Diphosphonate Bone Scan

Gerard¹,

Gerczuk²,

Idupuganti³

et al. 2008

Clinical Nuclear Medicine

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A 72-year-old man was hospitalized for transurethral resection of bladder cancer. Two days after the procedure, the patient continued to have gross hematuria and a computed tomography (CT) scan of the abdomen and pelvis with intravenous contrast was performed to check the integrity of the resection site. Later that day, the patient underwent technetium-99m methylene diphosphonate (MDP) bone scintigraphy to investigate the possibility of bone metastasis. The bone scan showed no signs of metastasis but did reveal increased uptake of the left hand and forearm on the opposite side of the injection site.

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Tc-99m Methylene Diphosphonate Uptake by Numerous Phleboliths in the Lower Extremity Detected Incidentally During Bone Scintigraphy

Sohn

Jeong²,

Lim³

et al. 2010

Clinical Nuclear Medicine

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Phleboliths are calcified thrombi within veins and very common in the veins of the lower part of the pelvis. Most adults have a small number of phleboliths. However, despite the high prevalence, phleboliths with increased uptake on bone scintigraphy have very rarely been reported in the literature. Tc-99m methylene diphosphonate bone scintigraphy was performed on a 46-year-old man with an abscess on the plantar surface of the left foot, which demonstrated incidental, irregular, mottled, increased uptake in the soft tissues of the left thigh and leg, which corresponded to numerous phleboliths on plain radiographs and CT.

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Extraosseous uptake of 99mTechnetium phosphate in an extremity

Cited by 3 publications

References 12 publications

Abnormally increased uptake of 18F-FDG in the forearm and hand following intra-arterial injection — hot forearm and hot hand signs

Abnormally increased uptake of 18F-FDG in the forearm and hand following intra-arterial injection — hot forearm and hot hand signs

Compartment Syndrome Caused by Computed Tomography Contrast Infiltration Seen on a Tc-99m Methylene Diphosphonate Bone Scan

Tc-99m Methylene Diphosphonate Uptake by Numerous Phleboliths in the Lower Extremity Detected Incidentally During Bone Scintigraphy

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