Extraordinary Pattern with Brain Metastasis of Ovarian Cancer with Five Cases: Survival Impact of Cranial Metastesectomy. Do or Not To Do?

Abstract

tastasis is low. Generally not including patients with brain metastases in drug indication studies. We created this series in order to contribute to the management of these patients based on literature. Materials and MethodsWe examined retrospectively the charts of patients with a diagnosis of ovarian cancer who had been treated between 2015-2018 at the Adana City Education and Research Hospital. All patients with a histologically confirmed diagnosis of ovarian carcinoma were included and other gynecologic cancers were excluded. Clinical records were reviewed and information on clinical and pathological data as well as treatment details were gathered. Literature review was conducted in PubMed. Studies in adult patients have been written in English and have been published in peer-reviewed journals as ovarian cancer and brain metastasis. ResultsIn our study, we analyzed retrospectively 92 patients who were followed up in Adana City Education and Research hospital with the diagnosis of ovarian cancer between 2015-2018. The median age of the patients was 59 (min: 25-max: 88). We detected cranial metastases in a total of 5 patients. The incidence of brain metastasis was 5.4%. The median age in patients with cranial metastases was 60 (min: 55-max: 66). Cranial metastesec-

Cutaneous and Cerebral Metastases From Primary Peritoneal Clear Cell Carcinoma

“…These can happen at the onset or during the evolution of the disease and they are frequently associated with hematogenous pathway and lymphatic invasion, with the less frequent locations being principally skin, bone, central nervous system (CNS), eye, breast, bronchus-trachea, heart-pericardium, rare lymph nodes and exceptionally unusual intraabdominal sites, often with poor prognosis [8]. The reported incidence for CNS metastasis ranges widely from 0.3 to 12% with an average of 2% [8,12] and the incidence of skin metastasis varies from 0.9 to 5.8% [7,8].…”