Extranodal lymphoplasmacytoid lymphoma: spectrum of disease

Guermazi, Ali; Meignin, Véronique; Brice, Pauline

doi:10.1007/s00330-002-1532-x

Cited by 3 publications

(1 citation statement)

References 30 publications

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“…HL accounts for 10%-35% of head and neck lymphomas, [1][2][3] and Waldeyer's ring is the most common site of involvement. [1][2][3][4][5] However, as extranodal involvement of HL manifests clinically in less than 1% of cases, 6 extranodal HL of the head and neck that does not involve Waldeyer's ring is extremely rare. 2,3,5 Waldeyer's ring is a common Epstein-Barr virus (EBV) reservoir and EBV is associated with some forms of malignant lymphoma, including Burkitt's lymphoma, HL, non-Hodgkin's lymphoma and immunodeficiency-associated lymphoproliferative disorders (LPDs).…”

Section: Introductionmentioning

confidence: 99%

Age-Related Epstein-Barr Virus-Positive Lymphoproliferative Disorders of the Orbit and Maxillary Sinus : A Case Report

Mitsui

Mawatari

Koiso

et al. 2012

J Clin Exp Hematopathol

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We report a rare case of age-related Epstein-Barr virus (EBV)-positive B-cell lymphoproliferative disorder (aEBVBLPD) primarily involving the orbit and maxillary sinus. Lesions in the left orbit and maxillary sinus were observed in a 59-year-old man presenting with pain in the left orbit and maxilla. Owing to the presence of Reed-Sternberg-like cells, the initial diagnosis was nodular sclerosis-type Hodgkin's lymphoma. Clinical stage was IIAE, and response to chemotherapy and radiotherapy was favorable. Further immunohistochemical and in situ hybridization analyses of the Reed-Sternberg-like giant cells revealed CD30, CD15, CD20, Bob-1, Oct-2, EBV-encoded RNAs (EBERs) and latent membrane protein-1 (LMP-1) expression. The characteristics of the present case, which included immunohistochemical findings, sites of primary lesions, absence of other lymph node lesions and relatively old age, suggested aEBVBLPD. Owing to the similarity in morphology, higher frequency at extranodal sites and poor prognosis, aEBVBLPD represents a differential diagnostic issue from classical Hodgkin's lymphoma when Reed-Sternberg cells are positive for EBV.

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Section: Introductionmentioning

confidence: 99%

Age-Related Epstein-Barr Virus-Positive Lymphoproliferative Disorders of the Orbit and Maxillary Sinus : A Case Report

Mitsui

Mawatari

Koiso

et al. 2012

J Clin Exp Hematopathol

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CT features of abdominal plasma cell neoplasms

et al. 2005

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The aim of this study was to describe the CT features of abdominal plasma cell neoplasms. We reviewed CT imaging findings in 11 patients (seven men, four women; mean age 62 years) with plasma cell neoplasms and abdominal involvement. Helical CT of the entire abdomen and pelvis was performed following intravenous administration of contrast material. Images were analyzed in consensus by two radiologists. Diagnoses were made from biopsy, surgery and/or clinical follow-up findings. Multiple myeloma was found in seven patients and extramedullary plasmacytoma in four patients. All patients with multiple myeloma had multifocal disease with involvement of perirenal space (4/7), retroperitoneal and pelvic lymph nodes (3/7), peritoneum (3/7), liver (2/7), subcutaneous tissues (2/7) and kidney (1/7). In three of the four patients with extramedullary plasmacytoma, a single site was involved, namely stomach, vagina and retroperitoneum. In the fourth patient, a double site of abdominal involvement was observed with rectal and jejunal masses. Plasma cell neoplasm should be considered in the differential diagnosis of single or multiple enhancing masses in the abdomen or pelvis. Abdominal plasma cell neoplasms were most frequently seen as well-defined enhancing masses (10/11).

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