Extranodal lymphoma of the head and neck: A 67-case series

Picard, A.; Cardinne, C.; Denoux, Yves; Wagner, I.; Chabolle, F.; Bach, C.

doi:10.1016/j.anorl.2014.07.005

Cited by 47 publications

(49 citation statements)

References 23 publications

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“…ENHL type of lymphoma affects patients with a median age of 68 years, with peak incidence in the 6th and 7th decades, although all ages may be concerned. Patients are more often male (Picarda et al, 2015).This is similar to the reported case. Lombard et al (2015) in the largest published series of 22 sinonasal lymphoma so far found that the presenting symptoms were poorly specific, with classic sinonasal functional signs: unilateral nasal obstruction, mucopurulent rhinorrhea, epistaxis and anosmia.…”

Section: Discussionsupporting

confidence: 79%

“…Lymphomas may originate from a lymph node or lymphatic tissue outside the lymph node (extranodal lymphomas). The extranodal lymphoma as mainly involve 4 sites: Waldeyer's ring, the nasal sinuses and fossae, the oral cavity and the salivary glands (Picarda et al, 2015). Lombard et al ( 2015) state that the main diagnostic problem is the lack of specific clinical signs, often leading to late consultation and thus diagnosis at an advanced stage.…”

Section: Introductionmentioning

confidence: 99%

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Lymphoma Maxilla mimicking orbital cellulitis; case report and review of Literature

et al. 2018

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Background: Sinonasal lymphomas are the commonest nonepithelial malignancies of the nasal cavity and paranasal sinuses. They may spread from their site of origin in nasal cavity and invade adjacent structures including orbits leading to varying presentation and a diagnostic dilemma. Case: A-77-year old Nepalese male presented with swelling of left eye since 1 month and pain in the same eye since 2 days. Observation: Examination revealed axial proptosis, swelling of lids, restricted extraocular movement, diffuse conjunctival and ciliary congestion with chemosis. Visual acuity was grossly decreased. The case was diagnosed as left orbital cellulitis and treated with broad spectrum intravenous antibiotics and oral steriods. There was no response despite 3 days of antibiotics and steroids therefore a computed tomography was planned which showed features of Sinonasal malignancy invading the orbit. Repeated biopsy was suggestive of malignant small round cell tumour. In the view of unclear preoperative biopsy indicating further details on the histologic type of tumor and extensive erosion of maxilla with complete loss of vision in the eye the patient was planned for Total Maxillectomy with Orbital extenteration of the left orbit. Post-operative histopathological and Immunohistochemical report were suggestive of High grade Lymphoma. The patient was advised for Adjuvant Chemotherapy and Radiotherapy, which the patient refused due to financial constraints. He is on occasional follow up since the last 6 months. Conclusions: The diagnosis of maxillary sinus lymphoma needs to be borne in mind when a clinician encounters a case of Orbital Cellulitis. It may be difficult to diagnose clinically and require radio-pathological correlation.

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Section: Discussionsupporting

confidence: 79%

Section: Introductionmentioning

confidence: 99%

Lymphoma Maxilla mimicking orbital cellulitis; case report and review of Literature

et al. 2018

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“…28 While this multi-center Italian study does not provide additional insight into the incidence of ENKTL-NT in Europe, it is one of the few studies with only non-Hispanic whites. In contrast to the scarcity of ENKTL-NT reported throughout Europe, relatively large retrospective ENKTL-NT studies 26,27 and a prospective clinical trial have been completed in France. 29 This suggests that ENKTL-NT may be more infrequent, underreported, or misdiagnosed in certain parts of Europe compared to France.…”

Section: Estimating Global Incidence Rates Of Enktl-ntmentioning

confidence: 99%

Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases

Haverkos

Pan

Gru

et al. 2016

Curr Hematol Malig Rep

159

222

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Extranodal NK/T-cell lymphoma, nasal type (ENKTL-NT) is an aggressive extranodal non-Hodgkin lymphoma most commonly occurring in East Asia and Latin America but with increasing incidence in the U.S. Data on epidemiology, disease presentation, and outcome for European and North American (“Western”) cases are very limited. We review published landmark clinical studies on ENKTL-NT in the West and report in detail recent data, including our institutional experience. We highlight key observations in its epidemiology, natural history, and trends in clinical management. In the U.S., ENKTL-NT is more common among Asian Pacific Islanders (API) and Hispanics compared to non-Hispanic whites. Published studies indicate less heterogeneity in clinical presentation in Western ENKTL-NT compared to Asian patients. While there is variation in age at diagnosis, presence of antecedent lymphoproliferative disorders, and outcomes among racial/ethnic groups, the universal association of ENKTL-NT with EBV and the poor response of this neoplasm to anthracycline-based therapy are consistent across all geographic areas.

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“…RT'nin overlere etkisi yaşla azalır. Çocukluk çağında fertilitenin ve hormonal işlevle-rin sürdürülebilmesi için overlerin korunması çok önemlidir (1,4,11) .…”

Section: Hh Sağaltımında Cerrahinin Yeriunclassified

“…Laparoskopi bir kamera portu ve iki çalışma portu ile yapılabilmektedir. Keith iğnesi ile bilateral utero-ovaryan bağlar ve uterus posteriorundan dikiş geçilerek, her iki overin uterus süpero-posterioruna sabitlenmesi, ters Y pelvik radyasyon alacak hastalarda uygulanabilir (1,11,12) . Overlerin her iki köşesine birer metalik klips konması RT'de kılavuz görevi görecektir.…”

Section: Hh Sağaltımında Cerrahinin Yeriunclassified

Lymphomas in childhood

Boybeyi¹,

Karnak²

2016

tcdd

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Extranodal lymphoma of the head and neck: A 67-case series

Abstract: ELHN is a rare pathology (5 cases per year in our department) of highly variable clinical presentation depending on location and histologic type. The ENT physician should be prepared for diagnosis regardless of anatomic location, so as to optimize diagnostic management.

Cited by 47 publications

References 23 publications

Lymphoma Maxilla mimicking orbital cellulitis; case report and review of Literature

Lymphoma Maxilla mimicking orbital cellulitis; case report and review of Literature

Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases

Lymphomas in childhood

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