Extranodal Lymphoma From Head to Toe: Part 1, The Head and Spine

Thomas, Adam G.; Vaidhyanath, Ram; Kirke, Rathy; Arora, Rajesh

doi:10.2214/ajr.10.7266

Cited by 34 publications

(32 citation statements)

References 22 publications

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“…Primary CNS lymphoma is rare, representing 1% of non-Hodgkin lymphoma cases. Intracranial involvement in patients with advanced, systemic lymphoma is more common, described in 10%-15% of cases (Fig 13) (20). The spectrum of imaging findings is broad.…”

Section: Review: Staging and Response Assessment In Lymphomamentioning

confidence: 99%

Imaging for Staging and Response Assessment in Lymphoma

et al. 2015

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Lymphoma comprises a heterogeneous group of diseases; remarkable advances have been made in diagnosis and treatment. Diagnostic imaging provides important information for staging and response assessment in patients with lymphoma. Over the years, staging systems have been refined, and dedicated criteria have been developed for evaluating response to therapy with both computed tomography (CT) and fluorine-18 fluorodeoxyglucose positron emission tomography (PET)/CT. The most recent system proposed for staging and response assessment, known as the Lugano classification, applies to both Hodgkin and non-Hodgkin lymphoma. The use of standardized criteria for staging and response assessment is important for making accurate treatment decisions and for determining the direction of further research. This review provides an overview of the updated CT and PET response criteria to familiarize the radiologist with the most important and clinically relevant aspects of lymphoma imaging. It also provides a short clinical update on lymphoma and the associated spectrum of imaging findings.

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Section: Review: Staging and Response Assessment In Lymphomamentioning

confidence: 99%

Imaging for Staging and Response Assessment in Lymphoma

et al. 2015

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“…2 MR spectroscopy can demonstrate evidence of increased cell turnover and decreased neuronal activity, ie, high choline peak, reversed choline / creatine ratio, and markedly low N-acetylaspartate. 2 These MR spectroscopy features are not pathognomonic for lymphoma; other pathologies such as glioma and cerebral metastasis can also demonstrate similar findings. Newer MRI techniques with perfusion-weighted imaging have been suggested to provide additional features to distinguish between lymphoma and other brain tumours.…”

Section: Nervous System Central Nervous Systemmentioning

confidence: 88%

“…In contrary, primary CNS lymphoma is rare and accounts for only 1% of all non-Hodgkin lymphoma. 2,3 Typical sites of involvement in the brain are corpus callosum, deep grey matter, and periventricular and subependymal regions. The radiological patterns of CNS lymphoma vary between immunocompetent and immunocompromised patients; the latter shows predilection to ring-like enhancement resulting from central necrosis of the lesion, whereas such a finding is uncommon in immunocompetent patients.…”

Section: Nervous System Central Nervous Systemmentioning

confidence: 99%

Multimodality Imaging Spectrum of Extranodal Lymphoma: A Pictorial Review

Tang¹,

Leung²,

Lee³

et al. 2019

Hong Kong J Radiol

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“…After contrast administration, the mass and the enlarged lymph nodes enhance homogeneously. Because necrotic lymph nodes and bone destruction are prevalent in carcinomas of the head and neck, their absence supports the diagnosis of a sporadic form of BL in a child (6).…”

Section: Head and Neck Involvementmentioning

confidence: 96%