“…Haematological, serological, skeletal survey and bone marrow examinations are expected to be normal. Electrophoretic serum globulins estimation may be elevated and serum immunoglobulins may be increased, but this may herald the onset of multiple myeloma; though abnormal serum protein electrophoretic patterns returned to normal after surgical removal of solitary lesions (Lane, 1952;Nelson and Lyons, 1957) and following response to radiotherapy in cases of solitary bone lesions (Meyer and Schulz, 1974). Investigations to exclude multiple myeloma are essential.…”